Introduction
ENTAVIR 1mgĀ is a higher-dose formulation ofĀ Entecavir, a potentĀ nucleoside analogue antiviralĀ used forĀ chronic hepatitis B (HBV) infection. It is specifically prescribed for:
-
Lamivudine-resistant HBV patients
-
HIV-coinfected HBV patientsĀ (who are not on HIV treatment)
Generic Name:Ā Entecavir
Brand Equivalents:Ā Baraclude (original), Entavir, Clevudine (in some regions)
Available Form:
-
Tablets:Ā 1 mg (white, film-coated)
-
Oral Solution:Ā 0.05 mg/mL
Uses of ENTAVIR 1mg
āĀ Chronic Hepatitis B (HBV) with prior lamivudine resistance
āĀ HBV patients with HIV co-infection (not on ART)
āĀ Compensated liver disease (cirrhosis, if stable)
Not for:
ā Acute hepatitis B
ā Hepatitis C (HCV) or other viruses
ā HIV treatment (only for HBV suppression)
Dosage & Administration
-
Standard Dose:Ā 1 mg once dailyĀ (for lamivudine-resistant or HIV-coinfected patients)
-
Empty Stomach:Ā TakeĀ at least 2 hours before or after mealsĀ for best absorption.
-
Missed Dose:Ā Take as soon as remembered, butĀ skip if close to next dose.
-
Do NOT stop abruptlyĀ ā Risk ofĀ severe HBV flare-up!
Side Effects
Common (Usually Mild):
-
Headache, dizziness
-
Fatigue
-
Mild nausea, diarrhea
Serious (Seek Medical Help):
-
Lactic acidosisĀ (muscle pain, rapid breathing, weakness)
-
Liver toxicityĀ (yellow skin, dark urine, confusion)
-
Kidney impairmentĀ (swelling, reduced urine output)
Storage Instructions
-
Room temperature (15ā30°C)
-
Keep away from moisture & light
-
Do not freezeĀ (for oral solution)
-
Keep out of childrenās reach
Why ENTAVIR 1mg is Important?
-
Strong HBV SuppressionĀ ā Very low resistance risk compared to older drugs.
-
Rescue TherapyĀ ā Effective forĀ lamivudine-resistant HBV cases.
-
Long-Term SafetyĀ ā Preferred forĀ years of treatmentĀ with fewer side effects.
-
Prevents Liver DamageĀ ā Reduces cirrhosis & liver cancer risk.
Precautions & Warnings
ā Ā HBV Flare RiskĀ ā Stopping suddenly can causeĀ life-threatening hepatitis.
ā Ā Kidney Monitoring NeededĀ ā Especially in elderly or dehydrated patients.
ā Ā Not a CureĀ ā Controls HBV but rarely eliminates it.
ā Ā Pregnancy & BreastfeedingĀ ā Use only if benefits outweigh risks.
Drug Interactions
-
HIV medications (e.g., Tenofovir)Ā ā May need dose adjustments.
-
Nephrotoxic drugs (NSAIDs, aminoglycosides)Ā ā Increased kidney risk
Reviews
There are no reviews yet.