Tenohep 300mg

Tenohep 300 mg is a medication that contains Tenofovir Disoproxil Fumarate (TDF) as its active ingredient. TDF is an antiviral medication that belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) and is primarily used for the treatment of HIV-1 infection and chronic hepatitis B virus (HBV) infection.

Key Information about Tenohep 300 mg (Tenofovir Disoproxil Fumarate):

Mechanism of Action:

• Inhibition of Reverse Transcriptase: Tenofovir Disoproxil Fumarate activates inside the cell and competes with the natural nucleotide substrates for incorporation into the viral DNA. Once incorporated, it leads to chain termination during the viral DNA synthesis, preventing the virus from replicating effectively.
• TDF has demonstrated efficacy against both HIV and HBV, making it a versatile option in the treatment of these viral infections.

Uses:

• HIV Treatment: Tenohep is used as part of a combination antiretroviral therapy regimen for the treatment of HIV-1 infection in adults and children.
• Hepatitis B Treatment: TDF is also indicated for the treatment of chronic hepatitis B virus infection in adults and pediatric patients.

Dosage and Administration:

• Dosage: The usual recommended dosage for Tenohep is 300 mg once daily for adults and children over the age of 12. The specific dosage may vary based on individual health conditions, renal function, and other factors as determined by a healthcare provider.
• Administration: Tenohep is taken orally, with or without food. Taking the medication at the same time every day helps maintain consistent drug levels in the body.

Side Effects:

While many people tolerate TDF well, some common side effects can include:

• Common Side Effects:
  • Nausea
  • Diarrhea
  • Headaches
  • Fatigue
  • Abdominal pain
• Serious Side Effects:
  • Kidney Problems: TDF can be associated with renal impairment, so regular monitoring of kidney function is recommended.
  • Bone Density Loss: Long-term use may lead to decreased bone mineral density and increased risk of fractures.
  • Liver Issues: Liver function should be monitored, particularly in patients with pre-existing liver disease, as TDF may cause liver enzyme elevation.

Recommendations:

• Regular Monitoring: Patients on Tenohep should have routine assessments of renal function, liver enzymes, and bone health.
• Adherence: It is essential to take Tenohep exactly as prescribed to maximize its effectiveness and reduce the risk of developing resistance.

As always, consult your healthcare provider for personalized medical advice, specific dosing recommendations, potential drug interactions, and management of side effects associated with Tenohep (Tenofovir Disoproxil Fumarate).