Tasigna 200mg

Tasigna 200mg is a prescription medication used to treat certain types of cancer, including chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It is a tyrosine kinase inhibitor that works by inhibiting the growth of cancer cells and reducing the production of new blood vessels that feed the tumor.

Composition:

• Tasigna 200mg: Nilotinib 200mg

Mechanism of Action:

Nilotinib, the active ingredient in Tasigna, is a tyrosine kinase inhibitor that works by:

1. Inhibiting the growth of cancer cells by blocking the action of specific enzymes that promote cell growth and division.
2. Reducing the production of new blood vessels that feed the tumor, which helps to reduce its growth and spread.
3. Inhibiting the activity of various signaling pathways that contribute to cancer cell growth and survival.

Indications:

Tasigna is approved for the treatment of:

1. Chronic myeloid leukemia (CML) in chronic phase (CP) or accelerated phase (AP) in patients who have not responded to other treatments.
2. Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) in patients who have not responded to other treatments.

Dosage:

The recommended dosage of Tasigna is:

• 200mg orally twice daily, taken at the same time every day.
• The recommended duration of treatment is until disease progression or unacceptable toxicity.

Side Effects:

Common side effects of Tasigna include:

1. Nausea
2. Vomiting
3. Diarrhea
4. Abdominal pain
5. Fatigue
6. Headache
7. Increased risk of bleeding or bruising
8. Skin rash
9. Hair loss
10. Muscle pain

Recommendation:

Tasigna is recommended for patients who have been diagnosed with CML or Ph+ ALL and have not responded to other treatments or have disease that has progressed after surgery and radiation therapy.

Important Note:

• Patients taking Tasigna should be closely monitored for signs of bleeding or bruising due to the risk of thrombocytopenia.
• Patients taking Tasigna should avoid taking medications that may increase the risk of bleeding or bruising.
• Pregnant or breastfeeding women should not use Tasigna, as it may harm the fetus or infant.
• Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Tasigna and to detect any potential side effects or complications.

Special Precautions:

• Patients with a history of kidney disease should be closely monitored for signs of worsening kidney function while taking Tasigna.
• Patients taking Tasigna should avoid taking medications that may interact with it, such as anticoagulants or medications that can increase blood pressure.
• Patients with a history of heart disease or high blood pressure should be closely monitored while taking Tasigna.

Contraindications:

• Patients with severe liver disease or severe kidney disease should not use Tasigna.
• Patients who are allergic to nilotinib or any other component of Tasigna should not use it.
• Patients who are pregnant or breastfeeding should not use Tasigna.