knilonat 200mg

Knilonat 200mg is a prescription medication used to treat certain types of cancer, including chronic myeloid leukemia (CML). It is a tyrosine kinase inhibitor that works by inhibiting the growth of cancer cells and reducing the production of new blood vessels that feed the tumor.

Composition:

• Knilonat 200mg: Nilotinib 200mg

Mechanism of Action:

Nilotinib, the active ingredient in Knilonat, is a tyrosine kinase inhibitor that works by:

1. Inhibiting the growth of cancer cells by blocking the action of specific enzymes that promote cell growth and division.
2. Reducing the production of new blood vessels that feed the tumor, which helps to reduce its growth and spread.

Indications:

Knilonat is approved for the treatment of:

1. Chronic myeloid leukemia (CML) in patients who have not responded to other treatments or have disease that has progressed after treatment with other medications.
2. CML in patients who have a T315I mutation in the BCR-ABL gene.

Dosage:

The recommended dosage of Knilonat is:

• 200mg orally twice daily, taken at the same time every day.
• The recommended duration of treatment is until disease progression or unacceptable toxicity.

Side Effects:

Common side effects of Knilonat include:

1. Fatigue
2. Nausea
3. Vomiting
4. Diarrhea
5. Abdominal pain
6. Constipation
7. Increased risk of bleeding or bruising
8. Skin rash
9. Hair loss
10. Muscle pain

Recommendation:

Knilonat is recommended for patients who have been diagnosed with CML and have not responded to other treatments or have disease that has progressed after surgery and radiation therapy.

Important Note:

• Patients taking Knilonat should be closely monitored for signs of bleeding or bruising due to the risk of thrombocytopenia.
• Patients taking Knilonat should avoid taking medications that may increase the risk of bleeding or bruising.
• Pregnant or breastfeeding women should not use Knilonat, as it may harm the fetus or infant.
• Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Knilonat and to detect any potential side effects or complications.

Special Precautions:

• Patients with a history of kidney disease should be closely monitored for signs of worsening kidney function while taking Knilonat.
• Patients taking Knilonat should avoid taking medications that may interact with it, such as anticoagulants or medications that can increase blood pressure.
• Patients with a history of heart disease or high blood pressure should be closely monitored while taking Knilonat.

Contraindications:

• Patients with severe liver disease or severe kidney disease should not use Knilonat.
• Patients who are allergic to nilotinib or any other component of Knilonat should not use it.
• Patients who are pregnant or breastfeeding should not use Knilonat.