Suninat 25mg

Suninat 25mg is a medication used to treat certain types of cancer, including gastrointestinal stromal tumors (GIST), advanced renal cell carcinoma (RCC), and pancreatic neuroendocrine tumors (pNET). It is a targeted therapy that works by inhibiting the growth of cancer cells.

Composition:

• Suninat 25mg: Sunitinib malate (25mg)

Mechanism of Action:

Sunitinib, the active ingredient in Suninat, is a tyrosine kinase inhibitor that works by:

1. Inhibiting the growth of cancer cells by blocking the action of protein kinases, which are enzymes that promote cell growth and division.
2. Inhibiting the formation of new blood vessels that feed the tumor, which helps to reduce its growth and spread.

Indications:

Suninat is approved for the treatment of:

1. Gastrointestinal stromal tumors (GIST) that cannot be treated with surgery or have spread to other parts of the body.
2. Advanced renal cell carcinoma (RCC) that has spread to other parts of the body.
3. Pancreatic neuroendocrine tumors (pNET) that have spread to other parts of the body.

Dosage:

The recommended dosage of Suninat is:

• GIST: 50mg orally once daily, taken continuously.
• RCC: 50mg orally once daily, taken continuously.
• pNET: 37.5mg orally once daily, taken continuously.

Side Effects:

Common side effects of Suninat include:

1. Fatigue
2. Diarrhea
3. Nausea
4. Abdominal pain
5. Vomiting
6. Hair loss
7. Increased risk of bleeding or bruising
8. High blood pressure

Recommendation:

Suninat is recommended for patients who have been diagnosed with GIST, RCC, or pNET and have not responded to other treatments or have disease that has progressed after surgery and radiation therapy.

Important Note:

• Patients taking Suninat should be closely monitored for signs of bleeding or bruising due to the risk of increased blood pressure.
• Patients taking Suninat should avoid taking medications that may increase the risk of bleeding or bruising.
• Pregnant or breastfeeding women should not use Suninat, as it may harm the fetus or infant.
• Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Suninat and to detect any potential side effects or complications.

Special Precautions:

• Patients with a history of kidney disease should be closely monitored for signs of worsening kidney function while taking Suninat.
• Patients taking Suninat should avoid taking medications that may interact with it, such as anticoagulants or medications that can increase blood pressure.
• Patients with a history of heart disease or high blood pressure should be closely monitored while taking Suninat.