Regonat 40mg

Regonat 40mg is a prescription medication used to treat certain types of cancer, including gastrointestinal stromal tumors (GIST), hepatocellular carcinoma (HCC), and colorectal cancer (CRC). It is a kinase inhibitor that works by blocking the growth of cancer cells.

Composition:

• Regonat 40mg: Regorafenib 40mg

Mechanism of Action:

Regorafenib, the active ingredient in Regonat, is a multikinase inhibitor that works by:

1. Inhibiting the growth of cancer cells by blocking the action of multiple protein kinases, which are enzymes that promote cell growth and division.
2. Inhibiting the formation of new blood vessels that feed the tumor, which helps to reduce its growth and spread.

Indications:

Regonat is approved for the treatment of:

1. Gastrointestinal stromal tumors (GIST) that have progressed after treatment with other medications.
2. Hepatocellular carcinoma (HCC) that has progressed after treatment with other medications.
3. Colorectal cancer (CRC) that has progressed after treatment with other medications.

Dosage:

The recommended dosage of Regonat is:

• 40mg orally once daily, taken with a meal and at the same time every day.
• The recommended duration of treatment is until disease progression or unacceptable toxicity.

Side Effects:

Common side effects of Regonat include:

1. Hand-foot syndrome
2. Fatigue
3. Diarrhea
4. Abdominal pain
5. Nausea
6. Vomiting
7. Increased risk of bleeding or bruising
8. High blood pressure
9. Skin rash
10. Hair loss

Recommendation:

Regonat is recommended for patients who have been diagnosed with GIST, HCC, or CRC and have not responded to other treatments or have disease that has progressed after surgery and radiation therapy.

Important Note:

• Patients taking Regonat should be closely monitored for signs of bleeding or bruising due to the risk of increased blood pressure.
• Patients taking Regonat should avoid taking medications that may increase the risk of bleeding or bruising.
• Pregnant or breastfeeding women should not use Regonat, as it may harm the fetus or infant.
• Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Regonat and to detect any potential side effects or complications.

Special Precautions:

• Patients with a history of kidney disease should be closely monitored for signs of worsening kidney function while taking Regonat.
• Patients taking Regonat should avoid taking medications that may interact with it, such as anticoagulants or medications that can increase blood pressure.
• Patients with a history of heart disease or high blood pressure should be closely monitored while taking Regonat.