Oxa 100 MG

Oxa 100 is a medication used to treat various types of cancer, including colon cancer, rectal cancer, and ovarian cancer. It is an injectable medication that works by inhibiting the growth of cancer cells and slowing down the progression of the disease.

Composition:

Oxa 100 is a solution of Oxaliplatin, a medication that is a platinum-based compound.

Indications:

Oxa 100 is indicated for the treatment of:

• Metastatic colorectal cancer
• Adjuvant treatment of colon cancer
• Metastatic gastric cancer
• Advanced or metastatic ovarian cancer

Mechanism of Action:

Oxaliplatin works by:

1. Binding to DNA and forming a complex that prevents the replication of DNA
2. Inhibiting the repair of DNA damage
3. Inducing apoptosis (cell death) in cancer cells

Dosage and Administration:

The recommended dosage of Oxa 100 is:

• 100mg/m² administered as a 2-hour intravenous infusion every 3 weeks
• The dose should be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Oxa 100 include:

1. Nausea and vomiting
2. Diarrhea
3. Fatigue
4. Neurotoxicity (peripheral neuropathy, numbness, tingling)
5. Alopecia (hair loss)
6. Hematological toxicity (low blood cell count)

Serious side effects can include:

1. Myelosuppression (low blood cell count)
2. Cardiac toxicity (heart failure, arrhythmias)
3. Pulmonary toxicity (lung damage)
4. Gastrointestinal perforation (hole in the stomach or intestine)

Contraindications:

Oxa 100 is contraindicated in patients with:

1. Severe kidney disease
2. Severe liver disease
3. Severe cardiac disease
4. Severe pulmonary disease

Precautions:

1. Patients with a history of kidney disease should be closely monitored while receiving Oxa 100.
2. Patients with a history of liver disease should be closely monitored while receiving Oxa 100.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea, vomiting, or diarrhea.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.

As with any medication, it is important to consult with a healthcare professional before taking Oxa 100, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.