Cabozanib 80mg

Cabozanib 80mg is a medication used to treat certain types of cancer, including renal cell carcinoma (RCC) and other types of kidney cancer. It is a tablet that works by inhibiting the activity of tyrosine kinases, which are proteins that help cancer cells grow and multiply.

Composition:

Cabozanib 80mg contains Cabozantinib, a medication that is a tyrosine kinase inhibitor.

Indications:

Cabozanib 80mg is indicated for the treatment of:

1. Renal cell carcinoma (RCC) in patients who have received prior therapy
2. Other types of kidney cancer, including papillary renal cell carcinoma and chromophobe renal cell carcinoma

Mechanism of Action:

Cabozantinib works by:

1. Inhibiting the activity of tyrosine kinases, which are proteins that help cancer cells grow and multiply
2. Reducing the production of vascular endothelial growth factor (VEGF), which is a protein that helps cancer cells grow and multiply
3. Inhibiting the activation of platelet-derived growth factor (PDGF), which is a protein that helps cancer cells grow and multiply

Dosage and Administration:

The recommended dosage of Cabozanib 80mg is:

• 80mg taken orally once daily, with or without food
• The dose should be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Cabozanib 80mg include:

1. Fatigue
2. Nausea and vomiting
3. Diarrhea
4. Abdominal pain
5. Hair loss
6. Skin rash
7. Muscle weakness

Serious side effects can include:

1. High blood pressure (hypertension)
2. Increased risk of bleeding
3. Increased risk of heart problems
4. Increased risk of liver damage

Contraindications:

Cabozanib 80mg is contraindicated in patients with:

1. Hypersensitivity to Cabozantinib or other tyrosine kinase inhibitors
2. Severe allergic reactions to human serum albumin or other components of the medication

Precautions:

1. Patients with a history of cardiac disease should be closely monitored while receiving Cabozanib 80mg.
2. Patients with a history of liver disease should be closely monitored while receiving Cabozanib 80mg.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of fatigue or nausea.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.

As with any medication, it is important to consult with a healthcare professional before taking Cabozanib 80mg, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.