Rolimus 5mg

Rolimus is a medication used to treat various types of cancer, including kidney, lung, and breast cancer. It is an oral medication that works by inhibiting the action of a protein called mTOR (mammalian target of rapamycin), which is involved in cell growth and division.

Composition:

Rolimus contains Everolimus, a medication that is a mTOR inhibitor.

Indications:

Rolimus is indicated for the treatment of:

1. Advanced kidney cancer (renal cell carcinoma)
2. Advanced lung cancer (non-small cell lung cancer)
3. Breast cancer (in combination with other medications)
4. Other types of cancer, including pancreatic neuroendocrine tumors and lymphoma

Mechanism of Action:

Everolimus works by:

1. Inhibiting the activity of mTOR, which is involved in cell growth and division
2. Blocking the growth and division of cancer cells
3. Reducing the production of vascular endothelial growth factor (VEGF), which is involved in the formation of new blood vessels

Dosage and Administration:

The recommended dosage of Rolimus is:

• 10mg taken orally once daily
• The dose should be taken with food
• The dose should be adjusted based on the patient’s response to treatment

Side Effects:

Common side effects of Rolimus include:

1. Stomatitis (mouth sores)
2. Nausea and vomiting
3. Fatigue
4. Diarrhea
5. Abdominal pain
6. Increased blood pressure
7. Edema (swelling)

Serious side effects can include:

1. Severe allergic reactions
2. Blood clots
3. Infections
4. Respiratory problems
5. Liver damage

Contraindications:

Rolimus is contraindicated in patients with:

1. Hypersensitivity to Everolimus
2. Severe liver or kidney disease
3. Pregnancy or breastfeeding
4. History of angioedema or other allergic reactions

Precautions:

1. Patients with a history of hypertension or edema should be closely monitored while receiving Rolimus.
2. Patients with a history of diabetes or kidney disease should be closely monitored while receiving Rolimus.
3. Patients with a history of liver disease should be closely monitored while receiving Rolimus.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of mouth sores or other side effects.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.