Cytoplatin is a medication used to treat various types of cancer, including ovarian, bladder, and lung cancer. It is an injectable medication that works by damaging the DNA of cancer cells, leading to cell death.
Composition:
Cytoplatin contains Cisplatin, a medication that is a platinum-based compound.
Indications:
Cytoplatin is indicated for the treatment of:
- Advanced ovarian cancer
- Bladder cancer
- Lung cancer
- Other types of cancer, including head and neck, esophageal, and cervical cancer
Mechanism of Action:
Cisplatin works by:
- Interacting with DNA and causing damage to the genetic material
- Inhibiting the repair of DNA damage, leading to cell death
- Inhibiting the growth and division of cancer cells
Dosage and Administration: The recommended dosage of Cytoplatin is:
- 50mg/m² administered as an intravenous infusion over 2 hours
- The dose should be repeated every 3-4 weeks or as directed by the healthcare provider
Side Effects:
Common side effects of Cytoplatin include:
- Nausea and vomiting
- Hair loss
- Fatigue
- Anemia (low red blood cell count)
- Neutropenia (low white blood cell count)
- Thrombocytopenia (low platelet count)
- Diarrhea
- Abdominal pain
Serious side effects can include:
- Severe allergic reactions
- Hemorrhagic cystitis (bleeding in the bladder)
- Ototoxicity (hearing loss)
- Neurotoxicity (nerve damage)
- Myelosuppression (reduced bone marrow function)
Contraindications:
Cytoplatin is contraindicated in patients with:
- Hypersensitivity to Cisplatin
- Severe kidney or liver disease
- Pregnancy or breastfeeding
- Recent or ongoing bleeding disorder
Precautions:
- Patients with a history of hearing loss or ototoxicity should be closely monitored while receiving Cytoplatin.
- Patients with a history of kidney or liver disease should be closely monitored while receiving Cytoplatin.
- Patients with a history of myelosuppression should be closely monitored while receiving Cytoplatin.
Patient Counseling:
- Patients should be counseled on the importance of taking their medication as directed and not missing doses.
- Patients should be instructed to report any signs of nausea or vomiting.
- Patients should be advised to report any changes in their appetite or weight loss.
Storage and Handling:
- Store at room temperature (20°C to 25°C) and protected from light.
- Do not freeze or expose to direct sunlight.
- Use within 24 months of opening.
Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.
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