Tegura

Tegura is a medication used to treat various types of cancer, including colon, breast, and lung cancer. It is an oral medication that works by blocking the production of nucleotides, which are essential for DNA synthesis and cell growth. Here are some key points about the product:

Composition:

Tegura contains Tegafur, a medication that is converted into 5-fluorouracil (5-FU) in the body. 5-FU is a chemotherapy agent that inhibits DNA synthesis and cell growth.

Indications:

Tegura is indicated for the treatment of:

1. Metastatic colorectal cancer
2. Metastatic breast cancer
3. Non-small cell lung cancer
4. Gastrointestinal cancer

Mechanism of Action:

Tegafur works by:

1. Being converted into 5-FU in the body, which inhibits DNA synthesis and cell growth
2. Blocking the production of nucleotides, which are essential for DNA synthesis and cell growth
3. Interfering with the repair of DNA damage, which can lead to cell death

Dosage and Administration: The recommended dosage of Tegura varies depending on the specific indication and patient population. However, the typical dosage is:

• 1-2 capsules taken orally twice daily, with or without food

Side Effects:

Common side effects of Tegura include:

1. Nausea and vomiting
2. Diarrhea
3. Fatigue
4. Hair loss
5. Anemia
6. Leukopenia (low white blood cell count)
7. Thrombocytopenia (low platelet count)

Serious side effects can include:

1. Severe allergic reactions
2. Gastrointestinal perforation
3. Hepatotoxicity (liver damage)
4. Neurotoxicity (nerve damage)

Contraindications:

Tegura is contraindicated in patients with:

1. Hypersensitivity to Tegafur
2. Pregnancy or breastfeeding
3. Severe liver or kidney disease
4. Active bleeding or bleeding disorder

Precautions:

1. Patients with a history of liver or kidney disease should be closely monitored while receiving Tegura.
2. Patients with a history of bleeding or bleeding disorders should be closely monitored while receiving Tegura.
3. Patients with a history of liver damage should be closely monitored while receiving Tegura.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea or vomiting.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.