Dacilon 0.5

Dacilon is a medication used to treat various types of cancer, including acute lymphoblastic leukemia, rhabdomyosarcoma, and Wilms’ tumor. It is a chemotherapy medication that is used to treat cancer. Here are some key points about the product:

Composition:

Dacilon contains Dactinomycin, a chemotherapy medication that is used to treat cancer.

Indications:

Dacilon is indicated for the treatment of:

1. Acute lymphoblastic leukemia (ALL)
2. Rhabdomyosarcoma (sarcoma)
3. Wilms’ tumor (nephroblastoma)
4. Ewing’s sarcoma
5. Soft tissue sarcoma

Mechanism of Action:

Dactinomycin works by:

1. Interfering with DNA synthesis and repair
2. Inhibiting the growth of cancer cells
3. Causing cell death

Dosage and Administration: The recommended dosage of Dacilon is:

• 0.5mg administered as a slow intravenous injection over 1-2 minutes
• The dose may be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Dacilon include:

1. Nausea and vomiting
2. Diarrhea
3. Fatigue
4. Low blood cell count (neutropenia, thrombocytopenia)
5. Increased risk of infections
6. Hair loss
7. Gastrointestinal toxicity

Serious side effects can include:

1. Severe allergic reactions
2. Bone marrow suppression
3. Pneumonia
4. Hemorrhagic cystitis
5. Pulmonary toxicity
6. Hepatotoxicity

Contraindications:

Dacilon is contraindicated in patients with:

1. Hypersensitivity to Dactinomycin
2. Severe kidney impairment
3. Severe liver impairment
4. Pregnancy or breastfeeding

Precautions:

1. Patients with a history of cardiac disease or cardiovascular risk factors should be closely monitored while receiving Dacilon.
2. Patients with a history of kidney disease or liver impairment should be closely monitored while receiving Dacilon.
3. Patients with a history of bleeding disorders should be closely monitored while receiving Dacilon.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea, vomiting, or diarrhea.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from moisture.
• Do not freeze or expose to direct sunlight.
• Use within 24 hours of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.