Tamodex 10mg

Tamodex is a brand name for Tamoxifen 20mg tablets, which is a medication used to treat various types of breast cancer and to prevent breast cancer in high-risk women. Here are some key points about the product:

Composition:

Each 20mg tablet of Tamodex contains Tamoxifen, a selective estrogen receptor modulator (SERM) that blocks the action of estrogen in the body, thereby preventing the growth and proliferation of breast cancer cells.

Indications:

Tamodex is indicated for:

1. Adjuvant treatment of breast cancer in women with estrogen-receptor-positive (ER+) tumors
2. Treatment of metastatic breast cancer in women with ER+ tumors
3. Prevention of breast cancer in women at high risk of developing the disease

Mechanism of Action:

Tamoxifen works by:

1. Binding to estrogen receptors in the breast tissue
2. Blocking the action of estrogen, which helps to prevent the growth and proliferation of breast cancer cells

Dosage and Administration:

The recommended dosage of Tamodex is 20mg taken orally, once a day, for the treatment of breast cancer. The dosage may be adjusted based on individual patient response and toxicity.

Side Effects:

Common side effects of Tamodex include:

1. Hot flashes
2. Nausea and vomiting
3. Diarrhea
4. Fatigue
5. Hair loss
6. Changes in menstrual cycle
7. Endometrial thickening
8. Cataracts

Serious side effects can include:

1. Endometrial cancer
2. Pulmonary embolism
3. Deep vein thrombosis
4. Stroke or transient ischemic attack
5. Liver dysfunction

Contraindications:

Tamodex is contraindicated in patients with:

1. Known hypersensitivity to tamoxifen
2. Active liver disease
3. Severe kidney disease
4. Pregnancy or breastfeeding (unless absolutely necessary)

Precautions:

1. Patients with a history of blood clots or stroke should be closely monitored while receiving Tamodex.
2. Patients with a history of liver disease or kidney dysfunction should receive dose reduction or close monitoring while receiving Tamodex.
3. Patients with a history of blood disorders should be closely monitored for signs of blood dyscrasias.
4. Women of childbearing potential should use effective contraception while receiving Tamodex.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of infection, such as fever, chills, or sore throat.
• Patients should be advised to report any changes in their menstrual cycle or vaginal bleeding.
• Patients should be informed that they may experience hot flashes, fatigue, or hair loss during treatment.

Storage and Handling:

• Store tablets at room temperature between 15°C and 30°C (59°F and 86°F).
• Do not expose to direct sunlight or moisture.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.