Zoclar 500mg TAB

**Zoclar** is another brand name for the antibiotic **Clarithromycin**, which is used to treat a wide range of bacterial infections. Each tablet typically contains **500 mg** of Clarithromycin as the active ingredient. ### PRODUCT DESCRIPTION **Clarithromycin** is part of the macrolide class of antibiotics and is effective against various gram-positive and some gram-negative bacteria. It disrupts bacterial protein synthesis, inhibiting the growth of bacteria. ### COMPOSITION – **Active Ingredient**: Clarithromycin – 500 mg – **Excipients**: Additional inactive substances included in the tablet formulation to aid in its stability, absorption, and overall effectiveness. ### MECHANISM OF ACTION Clarithromycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting mRNA translation and thereby preventing protein synthesis. This action leads to the bacterial cell’s inability to grow and reproduce. ### DOSAGE – **Adults**: The standard dosage for most infections is typically **250 mg to 500 mg** taken twice daily, depending on the type and severity of the infection. – **Severe Infections**: In certain cases, the dosage may be increased to **1,000 mg per day**. – **Duration of Treatment**: Usually varies from **5 to 14 days**, depending on the specific infection being treated. ### USES **Zoclar (Clarithromycin)** is commonly used for the treatment of: – Upper and lower respiratory tract infections (e.g., pneumonia, bronchitis, sinusitis) – Skin and soft tissue infections – Otitis media (middle ear infections) – Certain dental infections – As part of combination therapy for Helicobacter pylori eradication to reduce the risk of duodenal ulcers. ### SIDE EFFECTS Common side effects of Clarithromycin include: – Gastrointestinal symptoms (nausea, vomiting, diarrhea, abdominal pain) – Altered taste sensation – Headache – Rash More severe side effects, though rare, can include: – Allergic reactions (such as rash, itching, swelling) – Liver dysfunction (increased liver enzymes, jaundice) – QT interval prolongation, potentially leading to serious cardiac arrhythmias ### IMPORTANT NOTE – **Drug Interactions**: Clarithromycin can interact with other medications, such as certain statins, medications that affect liver enzymes, and anticoagulants. Always inform your healthcare provider about all medications you’re taking. – **Contraindications**: It’s contraindicated in individuals with known hypersensitivity to macrolide antibiotics and in those with certain heart conditions. – **Caution in Liver Disease**: Adjustments may be necessary for individuals with liver impairment or significant renal dysfunction. – **Pregnancy and Breastfeeding**: It is important to consult a healthcare provider before using Clarithromycin if pregnant or breastfeeding. ### RECOMMENDATION Patients should follow the dosing instructions provided by their healthcare provider carefully, complete the full course of the medication even if symptoms improve before finishing the course, and not take higher doses than prescribed. If a dose is missed, it should be taken as soon as remembered, unless it is close to the time for the next scheduled dose. Do not double doses. ### Disclaimer Always consult a healthcare professional for specific advice related to the use of **Zoclar (Clarithromycin)**, including its appropriateness for individual health needs and potential interactions with other medications.