Clariwok I.V

Here’s a structured product description for Clariwok (Clarithromycin Injection 500 mg): — ### PRODUCT DESCRIPTION **Clariwok** is a sterile injectable formulation of Clarithromycin, a macrolide antibiotic that provides broad-spectrum antibacterial activity. It is indicated for the treatment of a variety of infections caused by susceptible organisms, particularly in patients who cannot take oral medications. ### COMPOSITION Each vial of Clariwok contains: – **Clarithromycin**: 500 mg – **Excipients**: [e.g., sodium chloride, water for injection, or any other relevant ingredients] – **pH Adjuster**: [e.g., hydrochloric acid, if applicable] ### MECHANISM OF ACTION Clarithromycin exerts its antibacterial effects by binding to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis. This action disrupts bacterial growth and effectively treats infections caused by both gram-positive and certain gram-negative bacteria, as well as atypical pathogens. ### DOSAGE The recommended dosage of Clariwok varies depending on the type and severity of the infection: – **Adults**: Typically, the dose is **500 mg** administered by intravenous infusion every **12 hours**. In severe infections, doses may be adjusted to **1 g** every **12 hours**, based on clinical judgment and patient response. – **Duration of therapy** is usually **2 to 5 days**, depending on the type of infection and clinical response. – **Renal impairment**: Dosage adjustments may be required in patients with renal insufficiency. ### USES Clariwok is indicated for the treatment of: – Community-acquired pneumonia – Skin and soft tissue infections – Sinusitis and other respiratory tract infections – Infections caused by susceptible organisms when oral administration is not feasible ### SIDE EFFECTS Common side effects associated with Clariwok may include: – Nausea – Diarrhea – Abdominal pain – Headache – Taste disturbances Serious side effects, though less common, may include: – Hepatotoxicity (liver dysfunction) – Prolonged QT interval leading to arrhythmias – Allergic reactions (e.g., rash, anaphylaxis) Seek immediate medical attention if any severe reactions occur. ### IMPORTANT NOTE Clariwok is contraindicated in patients with a history of hypersensitivity to Clarithromycin, other macrolides, or any of the components in the formulation. Caution is advised in patients with liver disease and those on concurrent treatment with drugs that may prolong the QT interval or alter hepatic metabolism. ### RECOMMENDATION Complete the full course of Clariwok as prescribed by a healthcare provider. Monitor for effectiveness and potential side effects throughout the treatment period. Hydration and laboratory evaluations (e.g., liver function tests) may be necessary during therapy, particularly in patients with underlying liver conditions or those receiving prolonged treatment. — This information is intended as a general guide and should be tailored to meet specific guidelines, label requirements, and clinical practices relevant to your location or institution!