Description:
HERPERAX 800 mg is a higher-dose formulation of Acyclovir, an antiviral drug that works by inhibiting viral DNA replication. It is effective against herpes simplex virus (HSV-1, HSV-2) and varicella-zoster virus (VZV).
Storage:
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Store at room temperature (15-25°C).
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Protect from moisture and light.
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Keep out of reach of children.
Importance & Therapeutic Uses:
HERPERAX 800 mg is used for:
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Herpes Zoster (Shingles) – Reduces pain and speeds healing.
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Genital Herpes (HSV-2) – Treatment of outbreaks and suppression.
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Chickenpox (Varicella) – In severe cases or immunocompromised patients.
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Herpes Simplex Encephalitis (in combination with IV therapy).
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Prophylaxis in HIV/AIDS or Transplant Patients – Prevents herpes reactivation.
Dosage:
| Condition | Dosage | Duration |
|---|---|---|
| Shingles (Herpes Zoster) | 800 mg 5 times daily | 7-10 days |
| Genital Herpes (Initial) | 800 mg 3 times daily | 7-10 days |
| Recurrent Genital Herpes | 800 mg 2-3 times daily | 5 days |
| Chronic Suppression | 800 mg 2 times daily | Up to 12 months |
| Chickenpox (Adults) | 800 mg 4 times daily | 5 days |
Note:
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Renal dose adjustment needed for patients with kidney disease.
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Elderly patients may require lower doses.
Side Effects:
Common:
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Nausea, vomiting, diarrhea
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Headache, dizziness
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Fatigue, mild skin rash
Serious (Rare but Require Medical Attention):
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Kidney dysfunction (drink plenty of water)
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Neurological effects (confusion, hallucinations, tremors)
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Severe allergic reactions (swelling, itching, breathing difficulty)
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Liver enzyme abnormalities (monitored in long-term use)
Precautions & Warnings:
✔ Hydration is crucial – Prevents kidney damage.
✔ Not a cure – Reduces symptoms and transmission risk.
✔ Avoid in severe kidney disease (dose adjustment required).
✔ Pregnancy & Breastfeeding – Use only if benefits outweigh risks.
HERPERAX 800 mg is more suitable for severe herpes infections like shingles, while 400 mg is often used for milder cases.
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