valgan

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Introduction:

Valgan is an antiviral medication containing Valganciclovir, a prodrug of ganciclovir. It is primarily used to treat cytomegalovirus (CMV) infections, especially in immunocompromised patients (e.g., HIV/AIDS, organ transplant recipients).


Description:

  • Generic Name: Valganciclovir

  • Brand Name: Valgan

  • Drug Class: Antiviral (Nucleoside analogue)

  • Mechanism of Action:

    • Converts into ganciclovir, which inhibits CMV DNA polymerase, preventing viral replication.


Therapeutic Uses:

  1. CMV Retinitis (in HIV Patients)

  2. Prevention of CMV Disease in Organ Transplant Recipients

    • Kidney, heart, or pancreas transplants

  3. Congenital CMV Infection (in some cases)


Dosage:

Condition Dosage Duration
CMV Retinitis (Induction) 900 mg twice daily 21 days
CMV Retinitis (Maintenance) 900 mg once daily Long-term
CMV Prophylaxis (Transplant Patients) 900 mg once daily 100–200 days post-transplant
Renal Dose Adjustment Required (lower dose if impaired kidney function) As prescribed

Side Effects:

Common:

  • Bone Marrow Suppression (↓ Neutrophils, ↓ Platelets, ↓ Hemoglobin)

  • Diarrhea, nausea, vomiting

  • Fever, headache, fatigue

Serious (Require Medical Attention):

  • Severe neutropenia/pancytopenia (risk of infections/bleeding)

  • Kidney toxicity (monitor creatinine)

  • Seizures, hallucinations (CNS effects)

  • Retinal detachment (in CMV retinitis patients)


Important Warnings:

  • Hematologic Toxicity: Regular CBC monitoring required (risk of neutropenia, anemia, thrombocytopenia).

  • Teratogenic: Contraindicated in pregnancy (Category D – can cause fetal harm).

  • Carcinogenic/Mutagenic: Long-term use may increase cancer risk.

  • Drug Interactions:

    • Myelosuppressive drugs (e.g., zidovudine, trimethoprim-sulfamethoxazole) → Increased toxicity.

    • Probenecid → Increases ganciclovir levels.


Storage:

  • Store at 25°C (77°F), away from moisture.

  • Keep in original packaging (light-sensitive).

  • Keep out of reach of children & pets.


Conclusion:

Valgan (Valganciclovir) is a potent anti-CMV drug used in immunocompromised patients. Due to its high toxicity risk, strict monitoring of blood counts and kidney function is essential.

Would you like details on pediatric dosing or alternative CMV treatments?

Introduction:

Valgan is an antiviral medication containing Valganciclovir, a prodrug of ganciclovir. It is primarily used to treat cytomegalovirus (CMV) infections, especially in immunocompromised patients (e.g., HIV/AIDS, organ transplant recipients).


Description:

  • Generic Name: Valganciclovir

  • Brand Name: Valgan

  • Drug Class: Antiviral (Nucleoside analogue)

  • Mechanism of Action:

    • Converts into ganciclovir, which inhibits CMV DNA polymerase, preventing viral replication.


Therapeutic Uses:

  1. CMV Retinitis (in HIV Patients)

  2. Prevention of CMV Disease in Organ Transplant Recipients

    • Kidney, heart, or pancreas transplants

  3. Congenital CMV Infection (in some cases)


Dosage:

Condition Dosage Duration
CMV Retinitis (Induction) 900 mg twice daily 21 days
CMV Retinitis (Maintenance) 900 mg once daily Long-term
CMV Prophylaxis (Transplant Patients) 900 mg once daily 100–200 days post-transplant
Renal Dose Adjustment Required (lower dose if impaired kidney function) As prescribed

Side Effects:

Common:

  • Bone Marrow Suppression (↓ Neutrophils, ↓ Platelets, ↓ Hemoglobin)

  • Diarrhea, nausea, vomiting

  • Fever, headache, fatigue

Serious (Require Medical Attention):

  • Severe neutropenia/pancytopenia (risk of infections/bleeding)

  • Kidney toxicity (monitor creatinine)

  • Seizures, hallucinations (CNS effects)

  • Retinal detachment (in CMV retinitis patients)


Important Warnings:

  • Hematologic Toxicity: Regular CBC monitoring required (risk of neutropenia, anemia, thrombocytopenia).

  • Teratogenic: Contraindicated in pregnancy (Category D – can cause fetal harm).

  • Carcinogenic/Mutagenic: Long-term use may increase cancer risk.

  • Drug Interactions:

    • Myelosuppressive drugs (e.g., zidovudine, trimethoprim-sulfamethoxazole) → Increased toxicity.

    • Probenecid → Increases ganciclovir levels.


Storage:

  • Store at 25°C (77°F), away from moisture.

  • Keep in original packaging (light-sensitive).

  • Keep out of reach of children & pets.


Conclusion:

Valgan (Valganciclovir) is a potent anti-CMV drug used in immunocompromised patients. Due to its high toxicity risk, strict monitoring of blood counts and kidney function is essential.

Would you like details on pediatric dosing or alternative CMV treatments?

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions – 

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

Introduction:

Valgan is an antiviral medication containing Valganciclovir, a prodrug of ganciclovir. It is primarily used to treat cytomegalovirus (CMV) infections, especially in immunocompromised patients (e.g., HIV/AIDS, organ transplant recipients).


Description:

  • Generic Name: Valganciclovir

  • Brand Name: Valgan

  • Drug Class: Antiviral (Nucleoside analogue)

  • Mechanism of Action:

    • Converts into ganciclovir, which inhibits CMV DNA polymerase, preventing viral replication.


Therapeutic Uses:

  1. CMV Retinitis (in HIV Patients)

  2. Prevention of CMV Disease in Organ Transplant Recipients

    • Kidney, heart, or pancreas transplants

  3. Congenital CMV Infection (in some cases)


Dosage:

Condition Dosage Duration
CMV Retinitis (Induction) 900 mg twice daily 21 days
CMV Retinitis (Maintenance) 900 mg once daily Long-term
CMV Prophylaxis (Transplant Patients) 900 mg once daily 100–200 days post-transplant
Renal Dose Adjustment Required (lower dose if impaired kidney function) As prescribed

Side Effects:

Common:

  • Bone Marrow Suppression (↓ Neutrophils, ↓ Platelets, ↓ Hemoglobin)

  • Diarrhea, nausea, vomiting

  • Fever, headache, fatigue

Serious (Require Medical Attention):

  • Severe neutropenia/pancytopenia (risk of infections/bleeding)

  • Kidney toxicity (monitor creatinine)

  • Seizures, hallucinations (CNS effects)

  • Retinal detachment (in CMV retinitis patients)


Important Warnings:

  • Hematologic Toxicity: Regular CBC monitoring required (risk of neutropenia, anemia, thrombocytopenia).

  • Teratogenic: Contraindicated in pregnancy (Category D – can cause fetal harm).

  • Carcinogenic/Mutagenic: Long-term use may increase cancer risk.

  • Drug Interactions:

    • Myelosuppressive drugs (e.g., zidovudine, trimethoprim-sulfamethoxazole) → Increased toxicity.

    • Probenecid → Increases ganciclovir levels.


Storage:

  • Store at 25°C (77°F), away from moisture.

  • Keep in original packaging (light-sensitive).

  • Keep out of reach of children & pets.


Conclusion:

Valgan (Valganciclovir) is a potent anti-CMV drug used in immunocompromised patients. Due to its high toxicity risk, strict monitoring of blood counts and kidney function is essential.

Would you like details on pediatric dosing or alternative CMV treatments?

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Introduction:

Valgan is an antiviral medication containing Valganciclovir, a prodrug of ganciclovir. It is primarily used to treat cytomegalovirus (CMV) infections, especially in immunocompromised patients (e.g., HIV/AIDS, organ transplant recipients).


Description:

  • Generic Name: Valganciclovir

  • Brand Name: Valgan

  • Drug Class: Antiviral (Nucleoside analogue)

  • Mechanism of Action:

    • Converts into ganciclovir, which inhibits CMV DNA polymerase, preventing viral replication.


Therapeutic Uses:

  1. CMV Retinitis (in HIV Patients)

  2. Prevention of CMV Disease in Organ Transplant Recipients

    • Kidney, heart, or pancreas transplants

  3. Congenital CMV Infection (in some cases)


Dosage:

Condition Dosage Duration
CMV Retinitis (Induction) 900 mg twice daily 21 days
CMV Retinitis (Maintenance) 900 mg once daily Long-term
CMV Prophylaxis (Transplant Patients) 900 mg once daily 100–200 days post-transplant
Renal Dose Adjustment Required (lower dose if impaired kidney function) As prescribed

Side Effects:

Common:

  • Bone Marrow Suppression (↓ Neutrophils, ↓ Platelets, ↓ Hemoglobin)

  • Diarrhea, nausea, vomiting

  • Fever, headache, fatigue

Serious (Require Medical Attention):

  • Severe neutropenia/pancytopenia (risk of infections/bleeding)

  • Kidney toxicity (monitor creatinine)

  • Seizures, hallucinations (CNS effects)

  • Retinal detachment (in CMV retinitis patients)


Important Warnings:

  • Hematologic Toxicity: Regular CBC monitoring required (risk of neutropenia, anemia, thrombocytopenia).

  • Teratogenic: Contraindicated in pregnancy (Category D – can cause fetal harm).

  • Carcinogenic/Mutagenic: Long-term use may increase cancer risk.

  • Drug Interactions:

    • Myelosuppressive drugs (e.g., zidovudine, trimethoprim-sulfamethoxazole) → Increased toxicity.

    • Probenecid → Increases ganciclovir levels.


Storage:

  • Store at 25°C (77°F), away from moisture.

  • Keep in original packaging (light-sensitive).

  • Keep out of reach of children & pets.


Conclusion:

Valgan (Valganciclovir) is a potent anti-CMV drug used in immunocompromised patients. Due to its high toxicity risk, strict monitoring of blood counts and kidney function is essential.

Would you like details on pediatric dosing or alternative CMV treatments?

Reviews

There are no reviews yet.

Be the first to review “valgan”

Your email address will not be published. Required fields are marked *

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