Definition:
LOXICARD is a local anesthetic formulation, typically containing Lidocaine and Prilocaine (similar to EMLA), designed for topical numbing of skin and mucous membranes before minor medical or cosmetic procedures.
INTRODUCTION
LOXICARD is used to reduce pain during needle insertions (IVs, vaccinations), superficial surgeries, or dermatological treatments. It is valued for its efficacy, safety, and ease of application in clinical settings.
DESCRIPTION
Key Components:
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Lidocaine (2.5–5%) – Fast-acting sodium channel blocker.
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Prilocaine (2.5–5%) – Prolongs anesthetic effect.
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Optional Additives:
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Epinephrine (in some variants) – Extends duration via vasoconstriction.
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Liposomal carriers – Enhances skin penetration.
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Formulations:
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Cream, gel, or patch.
Onset & Duration:
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Onset: 15–30 minutes (faster than EMLA due to optimized absorption).
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Duration: 1–3 hours (depends on formulation).
USES
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Medical Procedures:
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IV cannulation, blood draws, suturing.
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Circumcision, catheter insertion.
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Dermatology/Cosmetic:
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Laser therapy (hair/tattoo removal), dermal fillers.
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Chemical peels, microneedling.
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Pediatrics:
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Painless vaccinations, heel sticks for neonates.
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SIDE EFFECTS
Common (Mild):
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Skin blanching, redness, or mild edema.
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Transient burning/itching.
Rare (Severe):
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Methemoglobinemia (prilocaine-related; monitor in infants).
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Allergic reactions (anaphylaxis – rare with amide anesthetics).
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Systemic toxicity (if overapplied: dizziness, seizures).
IMPORTANCE
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Pain Management:Â Enables tolerable procedures without injections.
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Pediatric-Friendly:Â Reduces trauma in children.
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Time-Efficient:Â Faster onset than traditional creams.
STORAGE
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Cool, dry place (20–25°C).
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Avoid freezing or direct sunlight.
CONCLUSION
LOXICARD is a versatile, effective topical anesthetic for minor procedures. Proper application time (30–60 mins under occlusion) and dose control are critical to prevent side effects.
Contraindications:
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Hypersensitivity to amide anesthetics.
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Open wounds/infected skin.
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Infants <12 months (unless prescribed).
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