THROMBOPAG 50

Anemia

Description
Shipping Options
Customer Reviews

Introduction

Thrombopag 50 is a 50 mg tablet formulation of eltrombopag, an oral thrombopoietin receptor agonist (TPO-RA). It works by stimulating platelet production in the bone marrow and is used to treat chronic immune thrombocytopenia (ITP), hepatitis C-associated thrombocytopenia, and severe aplastic anemia (SAA).

Storage

Store at 20–25°C (room temperature) in a dry place.
Keep tablets in their original blister pack to protect from moisture.
Do not refrigerate or freeze.

Dosage & Administration

1. Chronic ITP (Adults & Children ≥1 Year)

Starting Dose: 50 mg once daily (for most adults).
- Asian patients or those with liver impairment: 25 mg once daily (due to increased drug exposure).
Take on an empty stomach (1 hour before or 2 hours after food).
Avoid calcium-rich foods/drinks (milk, antacids) for at least 4 hours after dosing.
Adjust dose based on platelet response (target: 50–200 x 10⁹/L).

2. Hepatitis C-Associated Thrombocytopenia

Dose: 25 mg once daily (adjust based on platelet count).

3. Severe Aplastic Anemia (SAA)

Dose: 50 mg once daily (may increase to 75–100 mg if needed).

Clinical Significance

Increases platelet counts, reducing bleeding risk.
Reduces need for platelet transfusions and corticosteroids.
Oral administration (more convenient than injectable alternatives like romiplostim).
Effective in refractory cases where other treatments fail.

Drawbacks

Expensive long-term therapy.
Risk of excessive platelets → thrombosis (requires monitoring).
Not a cure (platelets may drop after stopping).
Food & drug interactions (must avoid calcium, iron, and antacids near dosing time).

Side Effects

Common Side Effects	Serious Side Effects
– Headache	– Blood clots (DVT, stroke, PE)
– Nausea	– Liver damage (monitor LFTs)
– Fatigue	– Bone marrow fibrosis (rare)
– Diarrhea	– Cataracts (eye exams needed)
– Rash	– Increased cancer risk (theoretical)

Drug Interactions

Antacids, calcium, iron supplements → Reduce absorption (take 4 hours apart).
Statins (atorvastatin, rosuvastatin) → Increased risk of myopathy.
Proton pump inhibitors (PPIs) → May reduce eltrombopag absorption.

Monitoring Requirements

Weekly platelet counts (until stable, then monthly).
Liver function tests (LFTs) before and during treatment.
Regular eye exams (risk of cataracts).

Conclusion

Thrombopag 50 (eltrombopag 50 mg) is a highly effective oral treatment for ITP, hepatitis C-related thrombocytopenia, and severe aplastic anemia. While it significantly improves platelet counts, it requires careful dosing adjustments, dietary restrictions, and monitoring for liver toxicity, thrombosis, and other risks. It is a valuable second-line therapy for patients unresponsive to conventional treatments.

Introduction

Storage

Store at 20–25°C (room temperature) in a dry place.
Keep tablets in their original blister pack to protect from moisture.
Do not refrigerate or freeze.

Dosage & Administration

1. Chronic ITP (Adults & Children ≥1 Year)

Starting Dose: 50 mg once daily (for most adults).
- Asian patients or those with liver impairment: 25 mg once daily (due to increased drug exposure).
Take on an empty stomach (1 hour before or 2 hours after food).
Avoid calcium-rich foods/drinks (milk, antacids) for at least 4 hours after dosing.
Adjust dose based on platelet response (target: 50–200 x 10⁹/L).

2. Hepatitis C-Associated Thrombocytopenia

Dose: 25 mg once daily (adjust based on platelet count).

3. Severe Aplastic Anemia (SAA)

Dose: 50 mg once daily (may increase to 75–100 mg if needed).

Clinical Significance

Increases platelet counts, reducing bleeding risk.
Reduces need for platelet transfusions and corticosteroids.
Oral administration (more convenient than injectable alternatives like romiplostim).
Effective in refractory cases where other treatments fail.

Drawbacks

Expensive long-term therapy.
Risk of excessive platelets → thrombosis (requires monitoring).
Not a cure (platelets may drop after stopping).
Food & drug interactions (must avoid calcium, iron, and antacids near dosing time).

Side Effects

Common Side Effects	Serious Side Effects
– Headache	– Blood clots (DVT, stroke, PE)
– Nausea	– Liver damage (monitor LFTs)
– Fatigue	– Bone marrow fibrosis (rare)
– Diarrhea	– Cataracts (eye exams needed)
– Rash	– Increased cancer risk (theoretical)

Drug Interactions

Antacids, calcium, iron supplements → Reduce absorption (take 4 hours apart).
Statins (atorvastatin, rosuvastatin) → Increased risk of myopathy.
Proton pump inhibitors (PPIs) → May reduce eltrombopag absorption.

Monitoring Requirements

Weekly platelet counts (until stable, then monthly).
Liver function tests (LFTs) before and during treatment.
Regular eye exams (risk of cataracts).

Conclusion

Shipping Options –

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions –

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

Description
Reviews (0)

Introduction

Storage

Store at 20–25°C (room temperature) in a dry place.
Keep tablets in their original blister pack to protect from moisture.
Do not refrigerate or freeze.

Dosage & Administration

1. Chronic ITP (Adults & Children ≥1 Year)

Starting Dose: 50 mg once daily (for most adults).
- Asian patients or those with liver impairment: 25 mg once daily (due to increased drug exposure).
Take on an empty stomach (1 hour before or 2 hours after food).
Avoid calcium-rich foods/drinks (milk, antacids) for at least 4 hours after dosing.
Adjust dose based on platelet response (target: 50–200 x 10⁹/L).

2. Hepatitis C-Associated Thrombocytopenia

Dose: 25 mg once daily (adjust based on platelet count).

3. Severe Aplastic Anemia (SAA)

Dose: 50 mg once daily (may increase to 75–100 mg if needed).

Clinical Significance

Increases platelet counts, reducing bleeding risk.
Reduces need for platelet transfusions and corticosteroids.
Oral administration (more convenient than injectable alternatives like romiplostim).
Effective in refractory cases where other treatments fail.

Drawbacks

Expensive long-term therapy.
Risk of excessive platelets → thrombosis (requires monitoring).
Not a cure (platelets may drop after stopping).
Food & drug interactions (must avoid calcium, iron, and antacids near dosing time).

Side Effects

Common Side Effects	Serious Side Effects
– Headache	– Blood clots (DVT, stroke, PE)
– Nausea	– Liver damage (monitor LFTs)
– Fatigue	– Bone marrow fibrosis (rare)
– Diarrhea	– Cataracts (eye exams needed)
– Rash	– Increased cancer risk (theoretical)

Drug Interactions

Antacids, calcium, iron supplements → Reduce absorption (take 4 hours apart).
Statins (atorvastatin, rosuvastatin) → Increased risk of myopathy.
Proton pump inhibitors (PPIs) → May reduce eltrombopag absorption.

Monitoring Requirements

Weekly platelet counts (until stable, then monthly).
Liver function tests (LFTs) before and during treatment.
Regular eye exams (risk of cataracts).

Conclusion

Reviews

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Description
Reviews (0)

Introduction

Storage

Store at 20–25°C (room temperature) in a dry place.
Keep tablets in their original blister pack to protect from moisture.
Do not refrigerate or freeze.

Dosage & Administration

1. Chronic ITP (Adults & Children ≥1 Year)

Starting Dose: 50 mg once daily (for most adults).
- Asian patients or those with liver impairment: 25 mg once daily (due to increased drug exposure).
Take on an empty stomach (1 hour before or 2 hours after food).
Avoid calcium-rich foods/drinks (milk, antacids) for at least 4 hours after dosing.
Adjust dose based on platelet response (target: 50–200 x 10⁹/L).

2. Hepatitis C-Associated Thrombocytopenia

Dose: 25 mg once daily (adjust based on platelet count).

3. Severe Aplastic Anemia (SAA)

Dose: 50 mg once daily (may increase to 75–100 mg if needed).

Clinical Significance

Increases platelet counts, reducing bleeding risk.
Reduces need for platelet transfusions and corticosteroids.
Oral administration (more convenient than injectable alternatives like romiplostim).
Effective in refractory cases where other treatments fail.

Drawbacks

Expensive long-term therapy.
Risk of excessive platelets → thrombosis (requires monitoring).
Not a cure (platelets may drop after stopping).
Food & drug interactions (must avoid calcium, iron, and antacids near dosing time).

Side Effects

Common Side Effects	Serious Side Effects
– Headache	– Blood clots (DVT, stroke, PE)
– Nausea	– Liver damage (monitor LFTs)
– Fatigue	– Bone marrow fibrosis (rare)
– Diarrhea	– Cataracts (eye exams needed)
– Rash	– Increased cancer risk (theoretical)

Drug Interactions

Antacids, calcium, iron supplements → Reduce absorption (take 4 hours apart).
Statins (atorvastatin, rosuvastatin) → Increased risk of myopathy.
Proton pump inhibitors (PPIs) → May reduce eltrombopag absorption.

Monitoring Requirements

Weekly platelet counts (until stable, then monthly).
Liver function tests (LFTs) before and during treatment.
Regular eye exams (risk of cataracts).

Conclusion

Reviews

There are no reviews yet.

Be the first to review “THROMBOPAG 50”

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