ARZEP

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1. Introduction

Arzep is a brand name for olopatadine, a dual-action ophthalmic solution with:

  • Potent antihistamine (H1-receptor antagonist)

  • Mast cell stabilizing properties

  • Anti-inflammatory effects

2. Key Specifications

  • Generic Name: Olopatadine hydrochloride

  • Brand Names: Arzep (India), Pataday (international)

  • Dosage Forms:

    • Eye drops (0.1%, 0.2%, 0.7% concentrations)

    • Nasal spray (also available in some markets)

  • Manufacturer: Sun Pharma (Arzep brand)

3. Therapeutic Advantages

✔ Dual mechanism (immediate + preventive action) ✔ 12-24 hour duration with single dose ✔ Minimal ocular side effects ✔ Suitable for long-term use

4. Mechanism of Action

  • H1-receptor antagonism (immediate relief)

  • Mast cell stabilization (prevents mediator release)

  • Inhibits:

    • Histamine release

    • TNF-α production

    • Eosinophil infiltration

5. Approved Indications

  • Allergic conjunctivitis

  • Vernal keratoconjunctivitis

  • Giant papillary conjunctivitis (off-label)

6. Dosage & Administration

Standard Dosing:

  • 0.1% solution: 1 drop in affected eye(s) BID

  • 0.2%/0.7% solution: 1 drop QD

  • Nasal spray: 2 sprays/nostril BID (if available)

Administration Tips:

  1. Wash hands before use

  2. Avoid touching dropper tip

  3. Wait 5 minutes between different eye medications

  4. Discard 4 weeks after opening

7. Safety Profile

Common ADRs (≤5%):

  • Mild burning/stinging (15-20%)

  • Headache (3-5%)

  • Dry eye (2-3%)

  • Bitter taste (nasal formulation)

Rare Effects:

  • Corneal edema

  • Eye pain

  • Allergic reactions

8. Pharmacokinetics

  • Onset: Within 3 minutes

  • Duration: Up to 24 hours (0.7% formulation)

  • Systemic absorption: Minimal (<0.01%)

9. Comparative Advantages

Parameter Olopatadine Ketotifen
Mechanism Dual Dual
Dosing QD-BID BID-QID
Burning Less More
Cost Higher Lower

10. Important Precautions

⚠ Contraindications:

  • Hypersensitivity to components

  • Contact lens use (wait 10 minutes after instillation)

⚠ Special Populations:

  • Pregnancy: Category C (use cautiously)

  • Children: Safe above 3 years

⚠ Drug Interactions:

  • Minimal systemic interactions

  • May potentiate other ocular sedatives

11. Storage Requirements

  • Store at 15-25°C

  • Keep bottle tightly closed

  • Protect from light

  • Do not freeze

12. Clinical Pearls

• First-line choice for moderate-severe allergic eye disease • Superior comfort compared to other antiallergy drops • Can be used seasonally or year-round • Consider 0.7% formulation for better compliance

13. Conclusion

Arzep provides effective, comfortable relief for allergic eye conditions through its unique dual mechanism. Its favorable safety profile and convenient dosing make it a preferred choice for both acute and chronic ocular allergy management.

1. Introduction

Arzep is a brand name for olopatadine, a dual-action ophthalmic solution with:

  • Potent antihistamine (H1-receptor antagonist)

  • Mast cell stabilizing properties

  • Anti-inflammatory effects

2. Key Specifications

  • Generic Name: Olopatadine hydrochloride

  • Brand Names: Arzep (India), Pataday (international)

  • Dosage Forms:

    • Eye drops (0.1%, 0.2%, 0.7% concentrations)

    • Nasal spray (also available in some markets)

  • Manufacturer: Sun Pharma (Arzep brand)

3. Therapeutic Advantages

✔ Dual mechanism (immediate + preventive action)
✔ 12-24 hour duration with single dose
✔ Minimal ocular side effects
✔ Suitable for long-term use

4. Mechanism of Action

  • H1-receptor antagonism (immediate relief)

  • Mast cell stabilization (prevents mediator release)

  • Inhibits:

    • Histamine release

    • TNF-α production

    • Eosinophil infiltration

5. Approved Indications

  • Allergic conjunctivitis

  • Vernal keratoconjunctivitis

  • Giant papillary conjunctivitis (off-label)

6. Dosage & Administration

Standard Dosing:

  • 0.1% solution: 1 drop in affected eye(s) BID

  • 0.2%/0.7% solution: 1 drop QD

  • Nasal spray: 2 sprays/nostril BID (if available)

Administration Tips:

  1. Wash hands before use

  2. Avoid touching dropper tip

  3. Wait 5 minutes between different eye medications

  4. Discard 4 weeks after opening

7. Safety Profile

Common ADRs (≤5%):

  • Mild burning/stinging (15-20%)

  • Headache (3-5%)

  • Dry eye (2-3%)

  • Bitter taste (nasal formulation)

Rare Effects:

  • Corneal edema

  • Eye pain

  • Allergic reactions

8. Pharmacokinetics

  • Onset: Within 3 minutes

  • Duration: Up to 24 hours (0.7% formulation)

  • Systemic absorption: Minimal (<0.01%)

9. Comparative Advantages

Parameter Olopatadine Ketotifen
Mechanism Dual Dual
Dosing QD-BID BID-QID
Burning Less More
Cost Higher Lower

10. Important Precautions

⚠ Contraindications:

  • Hypersensitivity to components

  • Contact lens use (wait 10 minutes after instillation)

⚠ Special Populations:

  • Pregnancy: Category C (use cautiously)

  • Children: Safe above 3 years

⚠ Drug Interactions:

  • Minimal systemic interactions

  • May potentiate other ocular sedatives

11. Storage Requirements

  • Store at 15-25°C

  • Keep bottle tightly closed

  • Protect from light

  • Do not freeze

12. Clinical Pearls

• First-line choice for moderate-severe allergic eye disease
• Superior comfort compared to other antiallergy drops
• Can be used seasonally or year-round
• Consider 0.7% formulation for better compliance

13. Conclusion

Arzep provides effective, comfortable relief for allergic eye conditions through its unique dual mechanism. Its favorable safety profile and convenient dosing make it a preferred choice for both acute and chronic ocular allergy management.

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions – 

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

1. Introduction

Arzep is a brand name for olopatadine, a dual-action ophthalmic solution with:

  • Potent antihistamine (H1-receptor antagonist)

  • Mast cell stabilizing properties

  • Anti-inflammatory effects

2. Key Specifications

  • Generic Name: Olopatadine hydrochloride

  • Brand Names: Arzep (India), Pataday (international)

  • Dosage Forms:

    • Eye drops (0.1%, 0.2%, 0.7% concentrations)

    • Nasal spray (also available in some markets)

  • Manufacturer: Sun Pharma (Arzep brand)

3. Therapeutic Advantages

✔ Dual mechanism (immediate + preventive action)
✔ 12-24 hour duration with single dose
✔ Minimal ocular side effects
✔ Suitable for long-term use

4. Mechanism of Action

  • H1-receptor antagonism (immediate relief)

  • Mast cell stabilization (prevents mediator release)

  • Inhibits:

    • Histamine release

    • TNF-α production

    • Eosinophil infiltration

5. Approved Indications

  • Allergic conjunctivitis

  • Vernal keratoconjunctivitis

  • Giant papillary conjunctivitis (off-label)

6. Dosage & Administration

Standard Dosing:

  • 0.1% solution: 1 drop in affected eye(s) BID

  • 0.2%/0.7% solution: 1 drop QD

  • Nasal spray: 2 sprays/nostril BID (if available)

Administration Tips:

  1. Wash hands before use

  2. Avoid touching dropper tip

  3. Wait 5 minutes between different eye medications

  4. Discard 4 weeks after opening

7. Safety Profile

Common ADRs (≤5%):

  • Mild burning/stinging (15-20%)

  • Headache (3-5%)

  • Dry eye (2-3%)

  • Bitter taste (nasal formulation)

Rare Effects:

  • Corneal edema

  • Eye pain

  • Allergic reactions

8. Pharmacokinetics

  • Onset: Within 3 minutes

  • Duration: Up to 24 hours (0.7% formulation)

  • Systemic absorption: Minimal (<0.01%)

9. Comparative Advantages

Parameter Olopatadine Ketotifen
Mechanism Dual Dual
Dosing QD-BID BID-QID
Burning Less More
Cost Higher Lower

10. Important Precautions

⚠ Contraindications:

  • Hypersensitivity to components

  • Contact lens use (wait 10 minutes after instillation)

⚠ Special Populations:

  • Pregnancy: Category C (use cautiously)

  • Children: Safe above 3 years

⚠ Drug Interactions:

  • Minimal systemic interactions

  • May potentiate other ocular sedatives

11. Storage Requirements

  • Store at 15-25°C

  • Keep bottle tightly closed

  • Protect from light

  • Do not freeze

12. Clinical Pearls

• First-line choice for moderate-severe allergic eye disease
• Superior comfort compared to other antiallergy drops
• Can be used seasonally or year-round
• Consider 0.7% formulation for better compliance

13. Conclusion

Arzep provides effective, comfortable relief for allergic eye conditions through its unique dual mechanism. Its favorable safety profile and convenient dosing make it a preferred choice for both acute and chronic ocular allergy management.

Reviews

There are no reviews yet.

Be the first to review “ARZEP”

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1. Introduction

Arzep is a brand name for olopatadine, a dual-action ophthalmic solution with:

  • Potent antihistamine (H1-receptor antagonist)

  • Mast cell stabilizing properties

  • Anti-inflammatory effects

2. Key Specifications

  • Generic Name: Olopatadine hydrochloride

  • Brand Names: Arzep (India), Pataday (international)

  • Dosage Forms:

    • Eye drops (0.1%, 0.2%, 0.7% concentrations)

    • Nasal spray (also available in some markets)

  • Manufacturer: Sun Pharma (Arzep brand)

3. Therapeutic Advantages

✔ Dual mechanism (immediate + preventive action)
✔ 12-24 hour duration with single dose
✔ Minimal ocular side effects
✔ Suitable for long-term use

4. Mechanism of Action

  • H1-receptor antagonism (immediate relief)

  • Mast cell stabilization (prevents mediator release)

  • Inhibits:

    • Histamine release

    • TNF-α production

    • Eosinophil infiltration

5. Approved Indications

  • Allergic conjunctivitis

  • Vernal keratoconjunctivitis

  • Giant papillary conjunctivitis (off-label)

6. Dosage & Administration

Standard Dosing:

  • 0.1% solution: 1 drop in affected eye(s) BID

  • 0.2%/0.7% solution: 1 drop QD

  • Nasal spray: 2 sprays/nostril BID (if available)

Administration Tips:

  1. Wash hands before use

  2. Avoid touching dropper tip

  3. Wait 5 minutes between different eye medications

  4. Discard 4 weeks after opening

7. Safety Profile

Common ADRs (≤5%):

  • Mild burning/stinging (15-20%)

  • Headache (3-5%)

  • Dry eye (2-3%)

  • Bitter taste (nasal formulation)

Rare Effects:

  • Corneal edema

  • Eye pain

  • Allergic reactions

8. Pharmacokinetics

  • Onset: Within 3 minutes

  • Duration: Up to 24 hours (0.7% formulation)

  • Systemic absorption: Minimal (<0.01%)

9. Comparative Advantages

Parameter Olopatadine Ketotifen
Mechanism Dual Dual
Dosing QD-BID BID-QID
Burning Less More
Cost Higher Lower

10. Important Precautions

⚠ Contraindications:

  • Hypersensitivity to components

  • Contact lens use (wait 10 minutes after instillation)

⚠ Special Populations:

  • Pregnancy: Category C (use cautiously)

  • Children: Safe above 3 years

⚠ Drug Interactions:

  • Minimal systemic interactions

  • May potentiate other ocular sedatives

11. Storage Requirements

  • Store at 15-25°C

  • Keep bottle tightly closed

  • Protect from light

  • Do not freeze

12. Clinical Pearls

• First-line choice for moderate-severe allergic eye disease
• Superior comfort compared to other antiallergy drops
• Can be used seasonally or year-round
• Consider 0.7% formulation for better compliance

13. Conclusion

Arzep provides effective, comfortable relief for allergic eye conditions through its unique dual mechanism. Its favorable safety profile and convenient dosing make it a preferred choice for both acute and chronic ocular allergy management.

Reviews

There are no reviews yet.

Be the first to review “ARZEP”

Your email address will not be published. Required fields are marked *

Medical Disclaimer

Anteka Pharmacy primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Anteka Pharmacy. Our mission is to support, not replace, the doctor-patient relationship.
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