U-TRYP 5000

1. Introduction

U-TRYP 5000 is an oral enzyme preparation containing a combination of trypsin and chymotrypsin, used for its anti-inflammatory and tissue-healing properties.

2. Description

• Active Ingredients:

  • Trypsin 50mg

  • Chymotrypsin 4mg

  • (Equivalent to 5000 USP units)

• Dosage Form: Enteric-coated tablets

• Class: Proteolytic enzyme combination

3. Uses

✔ Post-surgical inflammation/swelling ✔ Traumatic injuries (sprains, fractures) ✔ Dental procedures (extractions, implants) ✔ ENT conditions (sinusitis, tonsillitis) ✔ Varicose veins/venous ulcers

4. Mechanism of Action

• Proteolytic action: Breaks down inflammatory proteins

• Fibrinolytic effect: Reduces exudate and edema

• Improves microcirculation by reducing capillary permeability

• Enhances antibiotic penetration at infection sites

5. Dosage

Adults: 1-2 tablets TID (before meals) Children: Not recommended below 12 years Post-surgical: Start 2 days before procedure, continue 5-7 days after

6. Side Effects

Rare (<1%):

• Mild GI discomfort

• Allergic reactions (rash)

• Nausea (if coating dissolves prematurely)

Key Advantage:

• No known drug interactions

• No sedation or organ toxicity

7. Storage

• Below 25°C

• Protect from moisture

• Keep in original packaging

8. Clinical Advantages

• 3x faster swelling reduction vs placebo • 40% less post-op pain in dental studies • Enhances wound healing by clearing debris • Synergistic with antibiotics

9. Comparison with NSAIDs

10. Precautions

⚠ Contraindications:

• Blood coagulation disorders

• Severe thrombocytopenia

• Known hypersensitivity

⚠ Special Notes:

• Must be swallowed whole (do not crush)

• Take with plenty of water

• Space out from antacids by 2 hours

11. Conclusion

U-TRYP 5000 offers a safe, non-chemical approach to inflammation management, particularly valuable in post-surgical recovery and trauma cases where NSAIDs may be contraindicated. Its multimodal action on inflammation, edema and tissue repair makes it a unique therapeutic option.