LOX JELLY

1. Introduction

LOX Jelly is a topical anesthetic and lubricant containing Lidocaine Hydrochloride 2%. It is widely used in medical procedures to provide local numbing and procedural comfort, especially for mucosal surfaces.

2. Description

• Generic Name: Lidocaine Hydrochloride Jelly

• Active Ingredient: Lidocaine HCl 2% (20 mg/g)

• Formulation: Water-soluble, sterile lubricating gel

• Available Pack Sizes: 5g, 15g, 30g tubes

3. Uses

✔ Urethral catheterization (reduces discomfort) ✔ Endotracheal/nasogastric tube insertion ✔ Proctoscopy/sigmoidoscopy (anal anesthesia) ✔ Dental procedures (oral mucosa numbing) ✔ Minor gynecological exams (vaginal lubrication + anesthesia)

4. Mechanism of Action

• Blocks sodium channels in nerve fibers → prevents pain signal transmission

• Onset: 3–5 minutes (mucosal surfaces)

• Duration: 30–60 minutes

• Lubricating effect: Eases medical device insertion

5. Side Effects

Common (Mild & Temporary):

• Burning/stinging at application site

• Skin/mucosal blanching (reversible)

• Numbness beyond target area

Rare (Serious):

• Allergic reaction (rash, swelling)

• Systemic toxicity (if overused) → dizziness, seizures

• Methemoglobinemia (very rare, risk in infants)

6. Storage Instructions

• Temperature: Below 25°C

• Do not freeze

• Keep tube tightly closed

• Discard if discolored or expired

7. Precautions & Warnings

⚠ Contraindications:

• Allergy to lidocaine/amide anesthetics

• Open wounds/infected skin

• Severe liver disease

⚠ Special Cases:

• Children: Use minimal dose (risk of systemic absorption)

• Elderly: Higher sensitivity to lidocaine

• Pregnancy: Category B (use if benefits > risks)

⚠ Avoid:

• Applying near eyes

• Using with epinephrine-containing products

• Excessive doses (>4.5 mg/kg in adults)

8. Conclusion

LOX Jelly is a versatile, fast-acting anesthetic ideal for painless catheterization, endoscopy, and minor procedures. Its lubricating + numbing dual action improves patient comfort. However, strict dosing limits must be followed to avoid toxicity.

Best for:

• Hospitals & clinics for catheter insertions

• Dental practices for mucosal anesthesia

• Emergency settings for quick pain relief

Alternatives:

• Xylocaine Jelly (branded version)

• Lignocaine Gel (generic)