NEOVEC 10MG INJECTION

Anesthetics

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Definition: NEOVEC 10mg Injection is a novel amino-amide local anesthetic containing Ropivacaine Hydrochloride (10mg/mL), designed for prolonged nerve blocks with reduced cardiotoxicity compared to bupivacaine.

INTRODUCTION

NEOVEC is clinically preferred for:

Regional anesthesia (epidural, peripheral nerve blocks)
Post-operative pain management (up to 8 hours analgesia)
Labor analgesia (low-dose epidural infusions)

It offers differential sensory-motor blockade – numbing pain fibers while sparing motor function at lower doses.

DESCRIPTION

Composition:

Ropivacaine HCl (10mg/mL) – S(-)-enantiomer of bupivacaine
Preservative-free (single-dose vials)
pH 4.0–6.0 (adjusted for stability)

Key Properties:

Parameter	Value
Onset	10–20 minutes
Duration	4–8 hours (dose-dependent)
Protein Binding	94% (high)
Cardiac Safety	Lower risk than bupivacaine

USES

1. Surgical Anesthesia

Epidural: 15–30mg for C-sections
Peripheral blocks: 5–10mL (0.5–0.75%) for orthopedic surgeries

2. Pain Management

Continuous epidural infusion: 2mg/mL at 6–14mL/hr
TAP blocks: 20mL (0.2%) for abdominal surgeries

3. Pediatric Use

Caudal blocks: 1–2mg/kg (0.2% solution)

SIDE EFFECTS

Common (Dose-related):

Hypotension (neuraxial blocks)
Nausea (20% with epidurals)
Transient neurologic symptoms (1–2%)

Serious (Rare):

Cardiotoxicity (only at doses >250mg)
Seizures (plasma levels >4.5μg/mL)
Allergic reactions (cross-reactivity with other amides)

ADVANTAGES OVER BUPIVACAINE

Feature	NEOVEC (Ropivacaine)	Bupivacaine
Motor Block	Less intense	Profound
Cardiac Safety	Wider therapeutic window	Narrow margin
Vasoconstriction	Mild (reduced epi-need)	Significant

DOSAGE GUIDELINES

Application	Concentration	Volume (Max)	Onset	Duration
Epidural	0.5–1%	15–30mL	15min	3–6hrs
Nerve Block	0.2–0.75%	20–40mL	10min	6–8hrs
Infusion	0.1–0.2%	6–14mL/hr	–	Prolonged

Maximum Dose: 3mg/kg (up to 250mg)

STORAGE & HANDLING

Store at 20–25°C (excursions permitted 15–30°C)
Protect from light/freezing
Single-use only – Discard unused portions

CONTRAINDICATIONS

Hypersensitivity to amide local anesthetics
Severe hepatic impairment (reduced metabolism)
IV regional anesthesia (Bier block) – Risk of systemic toxicity

CONCLUSION

NEOVEC 10mg Injection combines: ✔ Longer action than lidocaine ✔ Safer profile vs bupivacaine ✔ Flexible dosing for surgical/pain applications

Critical Reminders:

Use test doses for epidural catheter placement
Monitor for CNS toxicity signs (tinnitus, metallic taste)
Lipid emulsion (Intralipid) must be available for toxicity management

Definition:
NEOVEC 10mg Injection is a novel amino-amide local anesthetic containing Ropivacaine Hydrochloride (10mg/mL), designed for prolonged nerve blocks with reduced cardiotoxicity compared to bupivacaine.

INTRODUCTION

NEOVEC is clinically preferred for:

Regional anesthesia (epidural, peripheral nerve blocks)
Post-operative pain management (up to 8 hours analgesia)
Labor analgesia (low-dose epidural infusions)

It offers differential sensory-motor blockade – numbing pain fibers while sparing motor function at lower doses.

DESCRIPTION

Composition:

Ropivacaine HCl (10mg/mL) – S(-)-enantiomer of bupivacaine
Preservative-free (single-dose vials)
pH 4.0–6.0 (adjusted for stability)

Key Properties:

Parameter	Value
Onset	10–20 minutes
Duration	4–8 hours (dose-dependent)
Protein Binding	94% (high)
Cardiac Safety	Lower risk than bupivacaine

USES

1. Surgical Anesthesia

Epidural: 15–30mg for C-sections
Peripheral blocks: 5–10mL (0.5–0.75%) for orthopedic surgeries

2. Pain Management

Continuous epidural infusion: 2mg/mL at 6–14mL/hr
TAP blocks: 20mL (0.2%) for abdominal surgeries

3. Pediatric Use

Caudal blocks: 1–2mg/kg (0.2% solution)

SIDE EFFECTS

Common (Dose-related):

Hypotension (neuraxial blocks)
Nausea (20% with epidurals)
Transient neurologic symptoms (1–2%)

Serious (Rare):

Cardiotoxicity (only at doses >250mg)
Seizures (plasma levels >4.5μg/mL)
Allergic reactions (cross-reactivity with other amides)

ADVANTAGES OVER BUPIVACAINE

Feature	NEOVEC (Ropivacaine)	Bupivacaine
Motor Block	Less intense	Profound
Cardiac Safety	Wider therapeutic window	Narrow margin
Vasoconstriction	Mild (reduced epi-need)	Significant

DOSAGE GUIDELINES

Application	Concentration	Volume (Max)	Onset	Duration
Epidural	0.5–1%	15–30mL	15min	3–6hrs
Nerve Block	0.2–0.75%	20–40mL	10min	6–8hrs
Infusion	0.1–0.2%	6–14mL/hr	–	Prolonged

Maximum Dose: 3mg/kg (up to 250mg)

STORAGE & HANDLING

Store at 20–25°C (excursions permitted 15–30°C)
Protect from light/freezing
Single-use only – Discard unused portions

CONTRAINDICATIONS

Hypersensitivity to amide local anesthetics
Severe hepatic impairment (reduced metabolism)
IV regional anesthesia (Bier block) – Risk of systemic toxicity

CONCLUSION

NEOVEC 10mg Injection combines:
✔ Longer action than lidocaine
✔ Safer profile vs bupivacaine
✔ Flexible dosing for surgical/pain applications

Critical Reminders:

Use test doses for epidural catheter placement
Monitor for CNS toxicity signs (tinnitus, metallic taste)
Lipid emulsion (Intralipid) must be available for toxicity management

Shipping Options –

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions –

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

Description
Reviews (0)

Definition:
NEOVEC 10mg Injection is a novel amino-amide local anesthetic containing Ropivacaine Hydrochloride (10mg/mL), designed for prolonged nerve blocks with reduced cardiotoxicity compared to bupivacaine.

INTRODUCTION

NEOVEC is clinically preferred for:

Regional anesthesia (epidural, peripheral nerve blocks)
Post-operative pain management (up to 8 hours analgesia)
Labor analgesia (low-dose epidural infusions)

It offers differential sensory-motor blockade – numbing pain fibers while sparing motor function at lower doses.

DESCRIPTION

Composition:

Ropivacaine HCl (10mg/mL) – S(-)-enantiomer of bupivacaine
Preservative-free (single-dose vials)
pH 4.0–6.0 (adjusted for stability)

Key Properties:

Parameter	Value
Onset	10–20 minutes
Duration	4–8 hours (dose-dependent)
Protein Binding	94% (high)
Cardiac Safety	Lower risk than bupivacaine

USES

1. Surgical Anesthesia

Epidural: 15–30mg for C-sections
Peripheral blocks: 5–10mL (0.5–0.75%) for orthopedic surgeries

2. Pain Management

Continuous epidural infusion: 2mg/mL at 6–14mL/hr
TAP blocks: 20mL (0.2%) for abdominal surgeries

3. Pediatric Use

Caudal blocks: 1–2mg/kg (0.2% solution)

SIDE EFFECTS

Common (Dose-related):

Hypotension (neuraxial blocks)
Nausea (20% with epidurals)
Transient neurologic symptoms (1–2%)

Serious (Rare):

Cardiotoxicity (only at doses >250mg)
Seizures (plasma levels >4.5μg/mL)
Allergic reactions (cross-reactivity with other amides)

ADVANTAGES OVER BUPIVACAINE

Feature	NEOVEC (Ropivacaine)	Bupivacaine
Motor Block	Less intense	Profound
Cardiac Safety	Wider therapeutic window	Narrow margin
Vasoconstriction	Mild (reduced epi-need)	Significant

DOSAGE GUIDELINES

Application	Concentration	Volume (Max)	Onset	Duration
Epidural	0.5–1%	15–30mL	15min	3–6hrs
Nerve Block	0.2–0.75%	20–40mL	10min	6–8hrs
Infusion	0.1–0.2%	6–14mL/hr	–	Prolonged

Maximum Dose: 3mg/kg (up to 250mg)

STORAGE & HANDLING

Store at 20–25°C (excursions permitted 15–30°C)
Protect from light/freezing
Single-use only – Discard unused portions

CONTRAINDICATIONS

Hypersensitivity to amide local anesthetics
Severe hepatic impairment (reduced metabolism)
IV regional anesthesia (Bier block) – Risk of systemic toxicity

CONCLUSION

NEOVEC 10mg Injection combines:
✔ Longer action than lidocaine
✔ Safer profile vs bupivacaine
✔ Flexible dosing for surgical/pain applications

Critical Reminders:

Use test doses for epidural catheter placement
Monitor for CNS toxicity signs (tinnitus, metallic taste)
Lipid emulsion (Intralipid) must be available for toxicity management

Reviews

There are no reviews yet.

Be the first to review “NEOVEC 10MG INJECTION”

Description
Reviews (0)

Definition:
NEOVEC 10mg Injection is a novel amino-amide local anesthetic containing Ropivacaine Hydrochloride (10mg/mL), designed for prolonged nerve blocks with reduced cardiotoxicity compared to bupivacaine.

INTRODUCTION

NEOVEC is clinically preferred for:

Regional anesthesia (epidural, peripheral nerve blocks)
Post-operative pain management (up to 8 hours analgesia)
Labor analgesia (low-dose epidural infusions)

It offers differential sensory-motor blockade – numbing pain fibers while sparing motor function at lower doses.

DESCRIPTION

Composition:

Ropivacaine HCl (10mg/mL) – S(-)-enantiomer of bupivacaine
Preservative-free (single-dose vials)
pH 4.0–6.0 (adjusted for stability)

Key Properties:

Parameter	Value
Onset	10–20 minutes
Duration	4–8 hours (dose-dependent)
Protein Binding	94% (high)
Cardiac Safety	Lower risk than bupivacaine

USES

1. Surgical Anesthesia

Epidural: 15–30mg for C-sections
Peripheral blocks: 5–10mL (0.5–0.75%) for orthopedic surgeries

2. Pain Management

Continuous epidural infusion: 2mg/mL at 6–14mL/hr
TAP blocks: 20mL (0.2%) for abdominal surgeries

3. Pediatric Use

Caudal blocks: 1–2mg/kg (0.2% solution)

SIDE EFFECTS

Common (Dose-related):

Hypotension (neuraxial blocks)
Nausea (20% with epidurals)
Transient neurologic symptoms (1–2%)

Serious (Rare):

Cardiotoxicity (only at doses >250mg)
Seizures (plasma levels >4.5μg/mL)
Allergic reactions (cross-reactivity with other amides)

ADVANTAGES OVER BUPIVACAINE

Feature	NEOVEC (Ropivacaine)	Bupivacaine
Motor Block	Less intense	Profound
Cardiac Safety	Wider therapeutic window	Narrow margin
Vasoconstriction	Mild (reduced epi-need)	Significant

DOSAGE GUIDELINES

Application	Concentration	Volume (Max)	Onset	Duration
Epidural	0.5–1%	15–30mL	15min	3–6hrs
Nerve Block	0.2–0.75%	20–40mL	10min	6–8hrs
Infusion	0.1–0.2%	6–14mL/hr	–	Prolonged

Maximum Dose: 3mg/kg (up to 250mg)

STORAGE & HANDLING

Store at 20–25°C (excursions permitted 15–30°C)
Protect from light/freezing
Single-use only – Discard unused portions

CONTRAINDICATIONS

Hypersensitivity to amide local anesthetics
Severe hepatic impairment (reduced metabolism)
IV regional anesthesia (Bier block) – Risk of systemic toxicity

CONCLUSION

NEOVEC 10mg Injection combines:
✔ Longer action than lidocaine
✔ Safer profile vs bupivacaine
✔ Flexible dosing for surgical/pain applications

Critical Reminders:

Use test doses for epidural catheter placement
Monitor for CNS toxicity signs (tinnitus, metallic taste)
Lipid emulsion (Intralipid) must be available for toxicity management

Reviews

There are no reviews yet.

Be the first to review “NEOVEC 10MG INJECTION”

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