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NEOVEC 20MG INJECTION

1. Introduction

NUMBEX is a topical anesthetic cream containing:

  • Lidocaine 2.5% (amide local anesthetic)

  • Prilocaine 2.5% (amide local anesthetic)

This eutectic mixture provides enhanced skin penetration for effective surface anesthesia prior to minor medical procedures.

2. Description

  • Generic Name: Lidocaine/Prilocaine cream

  • Brand Names: NUMBEX (India), EMLA (international brand)

  • Dosage Form: Topical cream in 5g/10g/30g tubes

  • Drug Class: Local anesthetic combination

3. Uses

✔ Pre-procedural anesthesia for:

  • Venipuncture

  • IV cannulation

  • Superficial surgical procedures

  • Laser treatments

  • Tattoo removal ✔ Pediatric pain management:

  • Vaccination pain relief

  • Circumcision (neonatal)

4. Mechanism of Action

  • Blocks voltage-gated sodium channels

  • Prevents nerve impulse conduction

  • Synergistic effect (lower melting point than individual components)

  • Onset: 30-60 minutes under occlusion

  • Duration: 1-2 hours after removal

5. Side Effects

Common (1-10%):

  • Application site reactions (pallor, redness, edema)

  • Mild burning/stinging

  • Temperature sensation changes

Serious (Rare):

  • Methemoglobinemia (especially in infants)

  • Systemic toxicity (with excessive application)

  • Allergic contact dermatitis

6. Storage

  • Temperature: Below 25°C

  • Do not freeze

  • Keep tube tightly closed

  • Shelf life: 2-3 years (check packaging)

7. Precautions & Warnings

⚠ Contraindications:

  • Congenital or idiopathic methemoglobinemia

  • Hypersensitivity to amide anesthetics

  • Application to broken skin/mucous membranes

⚠ Special Populations:

  • Infants <12 months: Higher methemoglobinemia risk

  • Pregnancy: Category B (use if clearly needed)

  • Elderly: More sensitive to systemic effects

⚠ Drug Interactions:

  • Class I antiarrhythmics: Additive cardiac effects

  • Sulfonamides: Increased methemoglobinemia risk

8. Application Guidelines

  1. Clean and dry application site

  2. Apply thick layer (1-2g per 10cm²)

  3. Cover with occlusive dressing

  4. Wait time:

    • Normal skin: 60 minutes

    • Genital mucosa: 15-30 minutes

  5. Maximum dose:

    • Adults: 20g

    • Children: 1g/kg (max 10g)

9. Conclusion

NUMBEX provides effective, predictable surface anesthesia for various minor procedures. Its eutectic formulation enhances skin penetration while maintaining safety. Particularly valuable for pediatric patients and needle-phobic individuals.

1. Introduction

NUMBEX is a topical anesthetic cream containing:

  • Lidocaine 2.5% (amide local anesthetic)

  • Prilocaine 2.5% (amide local anesthetic)

This eutectic mixture provides enhanced skin penetration for effective surface anesthesia prior to minor medical procedures.

2. Description

  • Generic Name: Lidocaine/Prilocaine cream

  • Brand Names: NUMBEX (India), EMLA (international brand)

  • Dosage Form: Topical cream in 5g/10g/30g tubes

  • Drug Class: Local anesthetic combination

3. Uses

✔ Pre-procedural anesthesia for:

  • Venipuncture

  • IV cannulation

  • Superficial surgical procedures

  • Laser treatments

  • Tattoo removal
    ✔ Pediatric pain management:

  • Vaccination pain relief

  • Circumcision (neonatal)

4. Mechanism of Action

  • Blocks voltage-gated sodium channels

  • Prevents nerve impulse conduction

  • Synergistic effect (lower melting point than individual components)

  • Onset: 30-60 minutes under occlusion

  • Duration: 1-2 hours after removal

5. Side Effects

Common (1-10%):

  • Application site reactions (pallor, redness, edema)

  • Mild burning/stinging

  • Temperature sensation changes

Serious (Rare):

  • Methemoglobinemia (especially in infants)

  • Systemic toxicity (with excessive application)

  • Allergic contact dermatitis

6. Storage

  • Temperature: Below 25°C

  • Do not freeze

  • Keep tube tightly closed

  • Shelf life: 2-3 years (check packaging)

7. Precautions & Warnings

⚠ Contraindications:

  • Congenital or idiopathic methemoglobinemia

  • Hypersensitivity to amide anesthetics

  • Application to broken skin/mucous membranes

⚠ Special Populations:

  • Infants <12 months: Higher methemoglobinemia risk

  • Pregnancy: Category B (use if clearly needed)

  • Elderly: More sensitive to systemic effects

⚠ Drug Interactions:

  • Class I antiarrhythmics: Additive cardiac effects

  • Sulfonamides: Increased methemoglobinemia risk

8. Application Guidelines

  1. Clean and dry application site

  2. Apply thick layer (1-2g per 10cm²)

  3. Cover with occlusive dressing

  4. Wait time:

    • Normal skin: 60 minutes

    • Genital mucosa: 15-30 minutes

  5. Maximum dose:

    • Adults: 20g

    • Children: 1g/kg (max 10g)

9. Conclusion

NUMBEX provides effective, predictable surface anesthesia for various minor procedures. Its eutectic formulation enhances skin penetration while maintaining safety. Particularly valuable for pediatric patients and needle-phobic individuals.

Shipping Options – 

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions – 

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

1. Introduction

NUMBEX is a topical anesthetic cream containing:

  • Lidocaine 2.5% (amide local anesthetic)

  • Prilocaine 2.5% (amide local anesthetic)

This eutectic mixture provides enhanced skin penetration for effective surface anesthesia prior to minor medical procedures.

2. Description

  • Generic Name: Lidocaine/Prilocaine cream

  • Brand Names: NUMBEX (India), EMLA (international brand)

  • Dosage Form: Topical cream in 5g/10g/30g tubes

  • Drug Class: Local anesthetic combination

3. Uses

✔ Pre-procedural anesthesia for:

  • Venipuncture

  • IV cannulation

  • Superficial surgical procedures

  • Laser treatments

  • Tattoo removal
    ✔ Pediatric pain management:

  • Vaccination pain relief

  • Circumcision (neonatal)

4. Mechanism of Action

  • Blocks voltage-gated sodium channels

  • Prevents nerve impulse conduction

  • Synergistic effect (lower melting point than individual components)

  • Onset: 30-60 minutes under occlusion

  • Duration: 1-2 hours after removal

5. Side Effects

Common (1-10%):

  • Application site reactions (pallor, redness, edema)

  • Mild burning/stinging

  • Temperature sensation changes

Serious (Rare):

  • Methemoglobinemia (especially in infants)

  • Systemic toxicity (with excessive application)

  • Allergic contact dermatitis

6. Storage

  • Temperature: Below 25°C

  • Do not freeze

  • Keep tube tightly closed

  • Shelf life: 2-3 years (check packaging)

7. Precautions & Warnings

⚠ Contraindications:

  • Congenital or idiopathic methemoglobinemia

  • Hypersensitivity to amide anesthetics

  • Application to broken skin/mucous membranes

⚠ Special Populations:

  • Infants <12 months: Higher methemoglobinemia risk

  • Pregnancy: Category B (use if clearly needed)

  • Elderly: More sensitive to systemic effects

⚠ Drug Interactions:

  • Class I antiarrhythmics: Additive cardiac effects

  • Sulfonamides: Increased methemoglobinemia risk

8. Application Guidelines

  1. Clean and dry application site

  2. Apply thick layer (1-2g per 10cm²)

  3. Cover with occlusive dressing

  4. Wait time:

    • Normal skin: 60 minutes

    • Genital mucosa: 15-30 minutes

  5. Maximum dose:

    • Adults: 20g

    • Children: 1g/kg (max 10g)

9. Conclusion

NUMBEX provides effective, predictable surface anesthesia for various minor procedures. Its eutectic formulation enhances skin penetration while maintaining safety. Particularly valuable for pediatric patients and needle-phobic individuals.

Reviews

There are no reviews yet.

Be the first to review “NUMBEX”

Your email address will not be published. Required fields are marked *

1. Introduction

NUMBEX is a topical anesthetic cream containing:

  • Lidocaine 2.5% (amide local anesthetic)

  • Prilocaine 2.5% (amide local anesthetic)

This eutectic mixture provides enhanced skin penetration for effective surface anesthesia prior to minor medical procedures.

2. Description

  • Generic Name: Lidocaine/Prilocaine cream

  • Brand Names: NUMBEX (India), EMLA (international brand)

  • Dosage Form: Topical cream in 5g/10g/30g tubes

  • Drug Class: Local anesthetic combination

3. Uses

✔ Pre-procedural anesthesia for:

  • Venipuncture

  • IV cannulation

  • Superficial surgical procedures

  • Laser treatments

  • Tattoo removal
    ✔ Pediatric pain management:

  • Vaccination pain relief

  • Circumcision (neonatal)

4. Mechanism of Action

  • Blocks voltage-gated sodium channels

  • Prevents nerve impulse conduction

  • Synergistic effect (lower melting point than individual components)

  • Onset: 30-60 minutes under occlusion

  • Duration: 1-2 hours after removal

5. Side Effects

Common (1-10%):

  • Application site reactions (pallor, redness, edema)

  • Mild burning/stinging

  • Temperature sensation changes

Serious (Rare):

  • Methemoglobinemia (especially in infants)

  • Systemic toxicity (with excessive application)

  • Allergic contact dermatitis

6. Storage

  • Temperature: Below 25°C

  • Do not freeze

  • Keep tube tightly closed

  • Shelf life: 2-3 years (check packaging)

7. Precautions & Warnings

⚠ Contraindications:

  • Congenital or idiopathic methemoglobinemia

  • Hypersensitivity to amide anesthetics

  • Application to broken skin/mucous membranes

⚠ Special Populations:

  • Infants <12 months: Higher methemoglobinemia risk

  • Pregnancy: Category B (use if clearly needed)

  • Elderly: More sensitive to systemic effects

⚠ Drug Interactions:

  • Class I antiarrhythmics: Additive cardiac effects

  • Sulfonamides: Increased methemoglobinemia risk

8. Application Guidelines

  1. Clean and dry application site

  2. Apply thick layer (1-2g per 10cm²)

  3. Cover with occlusive dressing

  4. Wait time:

    • Normal skin: 60 minutes

    • Genital mucosa: 15-30 minutes

  5. Maximum dose:

    • Adults: 20g

    • Children: 1g/kg (max 10g)

9. Conclusion

NUMBEX provides effective, predictable surface anesthesia for various minor procedures. Its eutectic formulation enhances skin penetration while maintaining safety. Particularly valuable for pediatric patients and needle-phobic individuals.

Reviews

There are no reviews yet.

Be the first to review “NUMBEX”

Your email address will not be published. Required fields are marked *

Medical Disclaimer

Anteka Pharmacy primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Anteka Pharmacy. Our mission is to support, not replace, the doctor-patient relationship.
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