**Lizolid 600** is a brand name for **Linezolid**, an antibiotic used to treat certain bacterial infections. Each tablet typically contains **600 mg** of Linezolid as the active ingredient.
### PRODUCT DESCRIPTION
**Linezolid** is part of the oxazolidinone class of antibiotics and is effective against a variety of gram-positive bacteria, including those that are resistant to other antibiotics, such as vancomycin-resistant Enterococcus (VRE) and methicillin-resistant Staphylococcus aureus (MRSA).
### COMPOSITION
– **Active Ingredient**: Linezolid – 600 mg
– **Excipients**: The tablet formulation may include inactive ingredients that aid in tablet formation and stability, which can vary by manufacturer.
### MECHANISM OF ACTION
Linezolid works by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, preventing the formation of a functioning 70S initiation complex, which is essential for bacterial growth and reproduction.
### DOSAGE
– **Adult Dosage**:
– The usual recommended dose is **600 mg taken orally every 12 hours** for a duration of **10 to 14 days**, depending on the infection being treated.
– Dosage may vary based on the specific condition being treated and patient factors.
### USES
**Lizolid (Linezolid 600 mg)** is indicated for:
– Pneumonia (including hospital-acquired pneumonia)
– Skin and soft tissue infections
– Vancomycin-resistant Enterococcus (VRE) infections
– Complicated or serious infections caused by certain resistant bacteria
### SIDE EFFECTS
Common side effects may include:
– Nausea and vomiting
– Diarrhea
– Headache
– Dizziness
– Insomnia
Serious side effects, though less common, can include:
– **Serotonin syndrome**: Particularly when combined with other serotonergic agents.
– **Anemia** and other blood dyscrasias: Long-term use can affect blood cell counts.
– **Peripheral neuropathy**: Prolonged therapy may lead to nerve damage.
– **Lactic acidosis**: A rare but serious side effect.
### IMPORTANT NOTE
– **Drug Interactions**: Linezolid can interact with medications that affect serotonin levels (e.g., SSRIs) and other medications, leading to increased risks of side effects. Inform your healthcare provider about all medications you are taking.
– **Contraindications**: Use caution in patients with a history of hypersensitivity to Linezolid or any of its components.
– **Monitoring**: It may be necessary to monitor blood counts with prolonged use.
### RECOMMENDATIONS
– **Adhere to the prescribed dosage** and complete the entire course of antibiotics, even if symptoms improve.
– **Monitor for side effects**, especially if on prolonged therapy, and report any significant issues to your healthcare provider.
– **If a dose is missed**, take it as soon as you remember; however, skip the missed dose if it’s almost time for the next dose.
### Disclaimer
Consult your healthcare provider for personalized medical advice regarding the use of **Lizolid (Linezolid 600 mg)**, including appropriate dosing, potential interactions, and necessary monitoring for side effects.
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