**Vivem 500 mg** is a formulation of **Meropenem**, a broad-spectrum carbapenem antibiotic used to treat a variety of serious bacterial infections. Each vial typically contains **500 mg** of Meropenem in powdered form, which is reconstituted for intravenous (IV) administration.
### PRODUCT DESCRIPTION
**Meropenem** is particularly effective against a wide range of gram-positive and gram-negative organisms, including many strains that are resistant to other classes of antibiotics. It is known for its effectiveness in severe infections.
### COMPOSITION
– **Active Ingredient**: Meropenem – 500 mg
– **Excipients**: The specific formulation may include stabilizers or other inactive ingredients, depending on the manufacturer.
### MECHANISM OF ACTION
Meropenem works by binding to penicillin-binding proteins (PBPs) in bacteria, inhibiting the synthesis of the bacterial cell wall, which ultimately leads to bacterial cell death. This broad-spectrum activity makes it crucial in treating serious infections.
### DOSAGE
– **Adult Dosage**:
– Commonly, for moderate to severe infections, the dosage is typically **500 mg to 1 g** administered every **8 hours**.
– For less severe infections, a longer dosing interval or lower dose may be appropriate based on the specific infection.
– **Administration**: Meropenem is given by **intravenous (IV) infusion** after reconstitution of the powder with a suitable diluent (as directed by the package insert or a healthcare provider).
– **Duration of Treatment**: Treatment duration generally ranges from **5 to 14 days**, depending on the type and severity of the infection and clinical response.
### USES
**Vivem (Meropenem 500 mg)** is indicated for conditions such as:
– Complicated intra-abdominal infections
– Complicated urinary tract infections
– Bacterial meningitis
– Skin and soft tissue infections
– Pneumonia, including hospital-acquired pneumonia
### SIDE EFFECTS
Common side effects include:
– Nausea and vomiting
– Diarrhea
– Rash or itching
– Injection site reactions (pain, redness, swelling)
Serious side effects, though rare, may include:
– Severe allergic reactions (including anaphylaxis)
– Seizures, particularly in patients with a history of seizures or CNS disorders
– Clostridium difficile-associated diarrhea
– Renal impairment
### IMPORTANT NOTE
– **Drug Interactions**: Inform your healthcare provider about all medications you are using to avoid potential interactions.
– **Contraindications**: Caution is advised in patients with a known allergy to beta-lactam antibiotics (penicillins or cephalosporins).
– **Caution in Renal Impairment**: Dose adjustments may be needed for patients with renal dysfunction.
### RECOMMENDATIONS
– Follow the healthcare provider’s instructions carefully regarding dosage and administration.
– Complete the full course of therapy as prescribed, even if symptoms improve before finishing the medication.
– Monitor for any severe adverse reactions or side effects and seek medical attention if necessary.
– If a dose is missed, contact a healthcare professional for guidance on how to proceed.
### Disclaimer
Consult your healthcare provider for personalized medical advice concerning the use of **Vivem (Meropenem 500 mg)**, including appropriate dosing, potential drug interactions, and necessary monitoring for side effects.
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