FAVIVIR

1. Product Description

Brand Name: Favivir Generic Name: Favipiravir Manufacturer: Hetero Drugs (India) Dosage Forms:

• 200mg tablets (most common)

• 400mg tablets (in some markets)

2. Composition

Active Ingredient:

• Favipiravir 200mg/400mg per tablet

Inactive Ingredients:

• Microcrystalline cellulose

• Povidone K30

• Croscarmellose sodium

• Magnesium stearate

• Film coating agents

3. Therapeutic Uses

Approved Indications:

• Treatment of mild to moderate COVID-19 in adults (emergency use authorization in India)

Mechanism of Action:

• RNA-dependent RNA polymerase inhibitor

• Prevents viral replication of SARS-CoV-2 and other RNA viruses

4. Recommended Dosage

COVID-19 Treatment Regimen:

• Day 1 (Loading Dose): 1800mg (9 tablets of 200mg) twice daily

• Days 2-10 (Maintenance): 800mg (4 tablets of 200mg) twice daily

• Total Duration: Typically 10-14 days

Administration:

• Take with or without food

• Swallow tablets whole with water

• Maintain consistent dosing intervals (every 12 hours)

5. Contraindications

• Pregnancy (Category X – high risk of fetal abnormalities)

• Severe hepatic impairment

• History of gout or hyperuricemia

• Hypersensitivity to favipiravir

6. Side Effects

Common:

• Nausea

• Headache

• Diarrhea

• Elevated uric acid levels

Serious (require medical attention):

• Severe liver dysfunction

• Allergic reactions

• Neuropsychiatric symptoms

7. Storage Conditions

• Store below 30°C

• Protect from moisture

• Keep in original packaging

• Shelf life: 24 months from manufacturing date

8. Important Precautions

• Pregnancy test required before treatment in women of childbearing potential

• Effective contraception required during and for 7 days after treatment

• Monitoring recommended:

  • Liver function tests

  • Uric acid levels

  • Clinical response