Aprezo 30 mg

Aprezo 30mg Apremilast 30mg Tablets is a medication used to treat:

• Plaque Psoriasis: a chronic autoimmune disease that causes red, scaly patches on the skin
• Psoriatic Arthritis: a chronic autoimmune disease that causes inflammation, stiffness, and pain in the joints

Composition: Each tablet of Aprezo contains 30mg of Apremilast (an active pharmaceutical ingredient), a phosphodiesterase 4 (PDE4) inhibitor.

Mechanism of Action: Apremilast works by:

• Inhibiting the activity of PDE4, an enzyme that breaks down cyclic adenosine monophosphate (cAMP)
• Increasing the levels of cAMP in the body, which reduces inflammation and immune responses
• Reducing the production of pro-inflammatory cytokines and chemokines

Dosage: The recommended dose of Aprezo is:

• 30mg twice daily, taken orally
• The dose should be adjusted according to patient response and tolerance

Side Effects: Common side effects of Aprezo include:

• Nausea or vomiting
• Diarrhea or abdominal pain
• Headache or fatigue
• Rash or itching
• Elevated liver enzymes

Rare but serious side effects include:

• Serious infections (e.g. tuberculosis, bacterial sepsis)
• Allergic reactions (e.g. anaphylaxis)
• Blood disorders (e.g. agranulocytosis, thrombocytopenia)
• Depression or suicidal thoughts

Recommendation: Aprezo is recommended for patients with plaque psoriasis or psoriatic arthritis who have not responded to other treatments or who have had unacceptable side effects. Patients with active infections, cancer, or a history of tuberculosis should be closely monitored while taking Aprezo.

Important Note:

• Aprezo should be used under the guidance of a healthcare provider with experience in the treatment of plaque psoriasis or psoriatic arthritis.
• Patients should be advised to report any symptoms of hypersensitivity reactions, such as rash, itching, swelling, or difficulty breathing.
• Aprezo may interact with other medications, such as antacids or anticonvulsants. Patients should inform their healthcare provider of all medications they are taking before starting Aprezo therapy.
• Patients with a history of kidney disease or other medical conditions that may affect their ability to respond to treatment should be closely monitored while taking Aprezo.

Special Precautions:

• Patients with active infections should be closely monitored while taking Aprezo.
• Patients with a history of tuberculosis should be evaluated for active tuberculosis before starting Aprezo therapy.
• Pregnant or breastfeeding women should consult their healthcare provider before taking Aprezo.
• Patients with a history of depression or suicidal thoughts should be closely monitored while taking Aprezo.

Indications:

• Plaque Psoriasis
• Psoriatic Arthritis

Contraindications:

• Active tuberculosis
• Severe infections
• Cancer
• Pregnancy and breastfeeding (unless medically necessary)

Note: The above information is a general summary and is not intended to provide individualized advice or recommendations. It is always best to consult a healthcare provider for personalized guidance on the use of Aprezo 30mg Apremilast 30mg Tablets.