Terifrac (Teriparatide 750mcg) is a prescription medication used to treat osteoporosis, a condition characterized by brittle and porous bones that can lead to fractures.
Composition:
Each 0.76 mL injection of Terifrac contains 750mcg of teriparatide, a recombinant human parathyroid hormone fragment. The injectable solution is sterile and preservative-free.
Mechanism of Action:
Terifrac works by stimulating the growth and activity of osteoblasts, the cells responsible for bone formation. This helps to increase bone density and strength, reducing the risk of fractures and osteoporotic-related complications.
Dosage:
The recommended dosage of Terifrac is 20mcg administered subcutaneously once daily. The injection should be given at the same time every day, and it’s essential to follow the dosage schedule as directed by your healthcare provider.
Uses:
Terifrac is indicated for the treatment of:
- Osteoporosis in postmenopausal women who are at high risk of fracture
- Osteoporosis in men who are at high risk of fracture
- Hypoparathyroidism (underactive parathyroid glands)
Side Effects:
Common side effects of Terifrac include:
- Injection site reactions (pain, swelling, redness)
- Nausea
- Vomiting
- Headache
- Dizziness
- Fatigue
- Muscle pain
- Back pain
Rare but serious side effects include:
- Osteosarcoma (bone cancer)
- Atypical subtrochanteric or diaphyseal femoral fractures (breaks in the thigh bone)
- Hypercalcemia (high levels of calcium in the blood)
- Allergic reactions (including anaphylaxis)
Recommendation:
Terifrac should be used under the guidance of a healthcare professional. Patients should be monitored regularly for changes in their bone density, as well as for signs of allergic reactions or other adverse events.
Important Note:
Terifrac is not recommended for use in:
- Patients with a history of osteosarcoma or other bone cancers
- Patients with a history of hypercalcemia or other calcium-related disorders
- Patients with a history of kidney disease or severe kidney impairment
- Patients with a history of liver disease or severe liver impairment
- Pregnant or breastfeeding women
Additionally, patients with a history of kidney stones or other kidney problems should be closely monitored while using Terifrac.
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