Cabtana is a brand name for Cabazitaxel, an injectable medication used to treat certain types of cancer. It is a microtubule inhibitor, which means it works by interfering with the growth and division of cancer cells.
Composition:
Each 60mg vial of Cabtana (Cabazitaxel) contains Cabazitaxel, a taxane derivative that works by inhibiting the growth of cancer cells.
Mechanism of Action: Cabazitaxel works by binding to the beta-tubulin subunit of microtubules, which are essential for the formation of the mitotic spindle. This leads to the disruption of microtubule dynamics, preventing the formation of a stable spindle and ultimately causing cell death.
Indications: Cabtana is used to treat:
- Metastatic castration-resistant prostate cancer (mCRPC) in combination with prednisone
- Breast cancer in combination with other chemotherapy agents
Dosage: The recommended dosage of Cabtana is:
- For mCRPC: 25 mg/m² every 3 weeks in combination with prednisone
- For breast cancer: 20-25 mg/m² every 3 weeks in combination with other chemotherapy agents
Side Effects: Common side effects of Cabtana include:
- Neutropenia (low white blood cell count)
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
- Fatigue
- Nausea and vomiting
- Diarrhea
- Constipation
- Abdominal pain
- Increased risk of infection
Recommendation: Cabtana should be used under the guidance of an experienced healthcare provider, usually an oncologist or urologist. Patients should be monitored for signs of side effects and toxicity.
Important Note:
- Cabtana can cause severe allergic reactions, including anaphylaxis.
- Patients with a history of severe allergic reactions or those who are taking immunosuppressive medications should be cautious when using Cabtana.
- Women of childbearing potential should avoid pregnancy during treatment with Cabtana due to the risk of fetal harm.
- Patients with pre-existing kidney or liver disease should be monitored closely during treatment with Cabtana due to the risk of worsening kidney or liver function.
It’s important to note that this information is intended to serve as a general overview of Cabtana and its uses, and should not be considered a substitute for medical advice from a qualified healthcare provider or oncologist.
It’s also important to note that Cabazitaxel is often used in combination with other medications, such as prednisone or other chemotherapy agents, and the specific dosage and regimen will depend on the individual patient’s needs and response to treatment.
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