Cacit 500mg

Cacit is a brand name for Capecitabine, an oral medication used to treat certain types of cancer. It is a prodrug that is converted into the active metabolite 5-fluorouracil (5-FU) in the body.

Composition:

Each 500mg tablet of Cacit contains Capecitabine, an antimetabolite that works by inhibiting the growth of cancer cells.

Mechanism of Action: Capecitabine works by inhibiting the growth of cancer cells by interfering with the synthesis of DNA and RNA. It does this by:

1. Inhibiting the enzyme thymidylate synthase, which is necessary for the production of thymidine, a nucleotide used in DNA synthesis.
2. Inhibiting the enzyme dihydrofolate reductase, which is necessary for the production of tetrahydrofolate, a coenzyme used in the synthesis of thymidine.

Indications: Cacit is used to treat:

1. Breast cancer in combination with other chemotherapy agents
2. Colorectal cancer in combination with other chemotherapy agents
3. Gastric cancer in combination with other chemotherapy agents

Dosage: The recommended dosage of Cacit is:

1. For breast cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day rest period
2. For colorectal cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day rest period
3. For gastric cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day rest period

Side Effects: Common side effects of Cacit include:

1. Hand-foot syndrome (palmar-plantar erythrodysesthesia)
2. Diarrhea
3. Nausea and vomiting
4. Abdominal pain
5. Fatigue
6. Increased risk of infection
7. Hair loss
8. Skin rash
9. Mouth sores

Recommendation: Cacit should be used under the guidance of an experienced healthcare provider, usually an oncologist or medical oncologist. Patients should be monitored for signs of side effects and toxicity.

Important Note:

• Cacit can cause severe allergic reactions, including anaphylaxis.
• Patients with a history of severe allergic reactions or those who are taking immunosuppressive medications should be cautious when using Cacit.
• Women of childbearing potential should avoid pregnancy during treatment with Cacit due to the risk of fetal harm.
• Patients with pre-existing kidney or liver disease should be monitored closely during treatment with Cacit due to the risk of worsening kidney or liver function.

It’s important to note that this information is intended to serve as a general overview of Cacit and its uses, and should not be considered a substitute for medical advice from a qualified healthcare provider or oncologist.

It’s also important to note that Capecitabine is often used in combination with other medications, such as other chemotherapy agents, and the specific dosage and regimen will depend on the individual patient’s needs and response to treatment.