Endoxan 50mg Tablet is a brand name for Cyclophosphamide, an oral medication used to treat various types of cancer, including leukemia, lymphoma, and breast cancer. It is also used to treat autoimmune disorders such as rheumatoid arthritis and lupus.
Composition:
Each Endoxan 50mg Tablet contains Cyclophosphamide, a alkylating agent that works by interfering with the replication of DNA in cancer cells.
Mechanism of Action: Cyclophosphamide works by inhibiting the growth of cancer cells and suppressing the immune system. It does this by:
- Interfering with DNA replication and cell division, making it difficult for cancer cells to grow and divide.
- Suppressing the immune system, reducing the production of immune cells and their ability to recognize and attack cancer cells.
Indications: Endoxan 50mg Tablet is used to treat:
- Acute lymphoblastic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Non-Hodgkin’s lymphoma
- Breast cancer
- Ovarian cancer
- Rheumatoid arthritis
- Lupus
Dosage: The recommended dosage of Endoxan 50mg Tablet varies depending on the condition being treated and the patient’s individual needs. The typical dosage range is:
- For cancer treatment: 10-50 mg/kg body weight every 4-6 weeks.
- For autoimmune disorders: 1-5 mg/kg body weight every day.
Side Effects: Common side effects of Endoxan 50mg Tablet include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Hair loss
- Increased risk of infection
- Increased risk of bleeding
- Skin rash
- Mouth sores
Recommendation: Endoxan 50mg Tablet should be used under the guidance of an experienced healthcare provider, usually an oncologist or hematologist. Patients should be monitored for signs of side effects and toxicity.
Important Note:
- Endoxan 50mg Tablet can cause severe allergic reactions, including anaphylaxis.
- Patients with a history of severe allergic reactions or those who are taking immunosuppressive medications should be cautious when using Endoxan 50mg Tablet.
- Women of childbearing potential should avoid pregnancy during treatment with Endoxan 50mg Tablet due to the risk of fetal harm.
- Patients with pre-existing kidney or liver disease should be monitored closely during treatment with Endoxan 50mg Tablet due to the risk of worsening kidney or liver function.
It’s important to note that this information is intended to serve as a general overview of Endoxan 50mg Tablet and its uses, and should not be considered a substitute for medical advice from a qualified healthcare provider or oncologist.
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