Enfiera 100 is a brand name for Rituximab, a chimeric monoclonal antibody that targets the CD20 antigen on the surface of B cells. It is used to treat certain types of non-Hodgkin lymphoma (NHL) and other B-cell
disorders.
Composition:
Each 100mg injection of Enfiera 100 Rituximab 100mg contains rituximab, a chimeric monoclonal antibody that targets the CD20 antigen on B cells.
Mechanism of Action: Rituximab works by binding to the CD20 antigen on B cells, leading to their destruction through a process called antibody-dependent cellular cytotoxicity (ADCC).
Use: Enfiera 100 is used to treat:
- Relapsed or refractory non-Hodgkin lymphoma (NHL) in combination with chemotherapy.
- Follicular lymphoma (FL) in combination with chemotherapy.
- Diffuse large B-cell lymphoma (DLBCL) in combination with chemotherapy.
Dosage: The recommended dosage of Enfiera 100 is:
- Relapsed or refractory NHL: 375 mg/m² as an intravenous infusion.
- Follicular lymphoma: 375 mg/m² as an intravenous infusion.
- Diffuse large B-cell lymphoma: 375 mg/m² as an intravenous infusion.
Side Effects: Common side effects of Enfiera 100 include:
- Infusion-related reactions
- Fatigue
- Headache
- Fever
- Chills
- Nausea
- Vomiting
- Diarrhea
- Rash
- Hypersensitivity reactions
Recommendation: Enfiera 100 should be administered under the guidance of an experienced healthcare provider, usually an oncologist or hematologist. Patients should be monitored for signs of infusion-related reactions or other side effects.
Important Note:
- Enfiera 100 may cause severe allergic reactions, including anaphylaxis.
- Patients with a history of severe allergic reactions or those who are taking immunosuppressive medications should be cautious when using Enfiera 100.
- Women of childbearing potential should avoid pregnancy during treatment with Enfiera 100 due to the risk of fetal harm.
- Patients with pre-existing kidney disease should be monitored closely during treatment with Enfiera 100 due to the risk of renal toxicity.
It’s important to note that this information is intended to serve as a general overview of Enfiera 100 and its uses, and should not be considered a substitute for medical advice from a qualified healthcare provider or oncologist.
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