Atranza is a prescription medication used to treat various types of cancer, including:
- Acute promyelocytic leukemia (APL)
- Other types of acute myeloid leukemia (AML)
Composition:
Atranza is a capsule containing 10mg of tretinoin.
Mechanism of Action:
Tretinoin works by:
- Inhibiting the growth and differentiation of cancer cells
- Inducing apoptosis (cell death) in cancer cells
Uses:
Atranza is used to treat:
- Acute promyelocytic leukemia (APL)
- Other types of acute myeloid leukemia (AML)
Dosage:
The recommended dosage of Atranza is:
- 10mg taken orally twice daily
- Continue treatment until the disease is in remission or unacceptable toxicity occurs
Side Effects:
Common side effects of Atranza include:
- Nausea and vomiting
- Diarrhea
- Headache
- Fatigue
- Skin rash
- Increased risk of infection
- Increased risk of bleeding
- Low white blood cell count
- Low platelet count
Recommendation:
Atranza is recommended for patients with APL or other types of AML who have not responded to other treatments. Patients should also be advised to monitor their blood counts and liver function regularly during treatment.
Important Note:
Patients should not take Atranza if they have a history of severe allergic reactions, liver problems, or kidney problems. Patients should also inform their healthcare provider if they have any underlying medical conditions, such as heart problems or lung problems, before taking Atranza.
Some common brands of tretinoin include:
- Vesanoid (Roche)
- All-Trans-Retinoic Acid (ATRA) (various manufacturers)
Please note that Atranza is not available in all markets and may be approved for different indications and dosages in different regions.
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