Leuben is a prescription medication used to treat certain types of cancer, including:
- B-cell lymphoma (a type of cancer that affects the immune system)
- Chronic lymphocytic leukemia (CLL) (a type of cancer that affects the white blood cells)
Composition:
Leuben is a clear, colorless solution containing 100mg of bendamustine per milliliter.
Mechanism of Action:
Bendamustine works by:
- Interfering with the growth and reproduction of cancer cells
- Damaging the genetic material of cancer cells, making it difficult for them to grow and divide
Uses:
Leuben is used to treat:
- B-cell lymphoma (a type of cancer that affects the immune system)
- Chronic lymphocytic leukemia (CLL) (a type of cancer that affects the white blood cells)
Dosage:
The recommended dosage of Leuben is:
- 100mg/m² body surface area administered intravenously over 30-40 minutes
- Repeat every 4-6 weeks, depending on the patient’s response to treatment
Side Effects:
Common side effects of Leuben include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Headache
- Dizziness
- Increased risk of infection
- Increased risk of bleeding
- Hair loss
- Skin rash
Recommendation:
Leuben is recommended for patients with B-cell lymphoma or CLL who have not responded to other treatments. Patients should also be advised to monitor their blood counts and liver function regularly during treatment.
Important Note:
Patients should not take Leuben if they have a history of severe allergic reactions, kidney problems, or liver problems. Patients should also inform their healthcare provider if they have any underlying medical conditions, such as heart problems or lung problems, before taking Leuben.
Some common brands of bendamustine include:
- Treanda (Cephalon)
- Bendamustine (Sanofi-Aventis)
Please note that Leuben is not available in all markets and may be approved for different indications and dosages in different regions.
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