BORTRAC 2MG INJ

A medication used to treat cancer!

Bortezumab (Bortezomib) 2mg (Velcade)

Product Description: Bortezumab is a prescription medicine used to treat:

1. Multiple myeloma (a type of blood cancer)
2. Mantle cell lymphoma (a type of non-Hodgkin’s lymphoma)

Composition: Bortezumab is a proteasome inhibitor that works by blocking the activity of the proteasome, a complex of enzymes that breaks down proteins in the cell.

Mechanism of Action: By blocking the proteasome, bortezumab:

1. Inhibits the degradation of certain proteins, leading to their accumulation and activation
2. Prevents the activation of key signaling pathways that promote cancer cell growth and survival

Dosage: The recommended dose of bortezumab is:

1. 2mg administered as an intravenous injection every 2 weeks
2. May be adjusted based on patient response and tolerability

Uses: Bortezumab is approved for the treatment of:

1. Multiple myeloma (a type of blood cancer)
2. Mantle cell lymphoma (a type of non-Hodgkin’s lymphoma)

Side Effects: Common side effects of bortezumab include:

1. Nausea and vomiting
2. Fatigue
3. Diarrhea
4. Constipation
5. Peripheral neuropathy (nerve damage)
6. Anemia
7. Thrombocytopenia (low platelet count)
8. Hypocalcemia (low calcium levels)

Recommendation: Bortezumab should be prescribed by a healthcare professional experienced in the treatment of cancer.

Important Note:

1. Bortezumab is not recommended for use in patients with severe kidney impairment or creatinine clearance <15 mL/min.
2. Patients with a history of allergic reactions to bortezumab or other proteasome inhibitors should not receive it.
3. Women who are pregnant or breastfeeding should not receive bortezumab.
4. Men who are taking bortezumab should use effective contraception to avoid fathering a child.

It’s essential to discuss any concerns or questions with your healthcare provider before starting bortezumab therapy.

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