AZACTIV 100MG INJ is a prescription medication used to treat various types of cancer, including acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is an intravenous injection that contains azacitidine, a medication that works by affecting the growth and development of cancer cells.
Composition:
Each vial of AZACTIV 100MG INJ contains 100mg of azacitidine.
Mechanism of Action:
Azacitidine works by affecting the growth and development of cancer cells. It does this by:
- Inhibiting the production of DNA and RNA, which are necessary for the growth and division of cancer cells
- Preventing the growth of new blood vessels that feed the cancer
- Inducing apoptosis (cell death) in cancer cells
Uses:
AZACTIV 100MG INJ is used to treat:
- Acute myeloid leukemia (AML) in patients who have not received prior therapy
- Myelodysplastic syndrome (MDS) in patients who have anemia and have not responded to other treatments
- Chronic myelomonocytic leukemia (CMML) in patients who have not received prior therapy
Dosage:
The recommended dosage of AZACTIV 100MG INJ is:
- 100mg administered as an intravenous injection over 30-60 minutes, repeated every 8 hours for 7 days, followed by a 7-day rest period
- The treatment cycle is repeated for a total of 4-6 cycles
Side Effects:
Common side effects of AZACTIV 100MG INJ include:
- Nausea
- Vomiting
- Fatigue
- Fever
- Chills
- Headache
- Dizziness
- Constipation
- Diarrhea
Recommendation:
AZACTIV 100MG INJ is recommended for patients who have not received prior therapy for acute myeloid leukemia or myelodysplastic syndrome. Patients should also be advised to drink plenty of water and to eat small, frequent meals during treatment to help reduce the risk of nausea and vomiting.
Important Note:
Patients should not take AZACTIV 100MG INJ if they have a history of severe allergic reactions, liver problems, or kidney problems. Patients should also inform their healthcare provider if they have any underlying medical conditions, such as heart problems or seizure disorders, before taking AZACTIV 100MG INJ.
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