Trazumab 440mg

Trazumab 440 is a medication used to treat certain types of breast cancer, including HER2-positive breast cancer. It is a sterile injection containing Trastuzumab, a humanized monoclonal antibody that targets the human epidermal growth factor receptor 2 (HER2).

Composition:

Trazumab 440 is a sterile injection containing Trastuzumab, a humanized monoclonal antibody.

Indications:

Trazumab 440 is indicated for the treatment of:

• HER2-positive breast cancer
• Breast cancer in combination with chemotherapy
• Breast cancer in combination with hormonal therapy

Mechanism of Action:

Trastuzumab works by:

1. Binding to the HER2 protein on the surface of cancer cells
2. Inhibiting the growth and proliferation of cancer cells
3. Inducing apoptosis (cell death) in cancer cells

Dosage and Administration:

The recommended dosage of Trazumab 440 is:

• 440mg administered as an intravenous infusion over 90 minutes every 3 weeks
• The dose should be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Trazumab 440 include:

1. Nausea and vomiting
2. Fatigue
3. Headache
4. Fever
5. Chills
6. Hypersensitivity reactions (rash, itching, hives)
7. Infusion reactions (chest tightness, difficulty breathing)

Serious side effects can include:

1. Cardiac toxicity (heart failure, arrhythmias)
2. Pulmonary toxicity (pneumonitis)
3. Neurotoxicity (seizures, neuropathy)
4. Hematological toxicity (anemia, neutropenia, thrombocytopenia)

Contraindications:

Trazumab 440 is contraindicated in patients with:

1. Severe cardiac disease
2. Severe liver disease
3. Severe kidney disease
4. Severe pulmonary disease

Precautions:

1. Patients with a history of cardiac disease should be closely monitored while receiving Trazumab 440.
2. Patients with a history of liver disease should be closely monitored while receiving Trazumab 440.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea, vomiting, or diarrhea.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.

As with any medication, it is important to consult with a healthcare professional before taking Trazumab 440, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.