OXA 50MG INJ is a medication used to treat certain types of cancer, including colorectal cancer, breast cancer, and ovarian cancer. It is a sterile injection containing Oxaliplatin, a platinum-based compound that works by inhibiting the growth of cancer cells.
Composition:
OXA 50MG INJ is a sterile injection containing Oxaliplatin, a platinum-based compound.
Indications:
OXA 50MG INJ is indicated for the treatment of:
- Colorectal cancer (in combination with fluorouracil and leucovorin)
- Breast cancer (in combination with fluorouracil and leucovorin)
- Ovarian cancer (in combination with carboplatin and paclitaxel)
Mechanism of Action:
Oxaliplatin works by:
- Binding to DNA and inhibiting the replication of cancer cells
- Preventing the repair of DNA damage
- Inducing apoptosis (cell death) in cancer cells
Dosage and Administration:
The recommended dosage of OXA 50MG INJ is:
- 50mg administered as an intravenous injection over 2-3 hours every 2 weeks
- The dose should be adjusted based on the patient’s response to treatment and tolerability
Side Effects:
Common side effects of OXA 50MG INJ include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Hair loss
- Muscle pain
- Joint pain
- Neurotoxicity (numbness, tingling, or weakness)
Serious side effects can include:
- Neutropenia (low white blood cell count)
- Thrombocytopenia (low platelet count)
- Anemia (low red blood cell count)
- Pulmonary toxicity (pneumonitis)
Contraindications:
OXA 50MG INJ is contraindicated in patients with:
- Severe bone marrow depression
- Severe liver disease
- Severe kidney disease
- Severe pulmonary disease
Precautions:
- Patients with a history of bone marrow depression should be closely monitored while receiving OXA 50MG INJ.
- Patients with a history of liver disease should be closely monitored while receiving OXA 50MG INJ.
Patient Counseling:
- Patients should be counseled on the importance of taking their medication as directed and not missing doses.
- Patients should be instructed to report any signs of nausea, vomiting, or diarrhea.
- Patients should be advised to report any changes in their appetite or weight loss.
Storage and Handling:
- Store at room temperature (20°C to 25°C) and protected from light.
- Do not freeze or expose to direct sunlight.
- Use within 24 months of opening.
Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.
As with any medication, it is important to consult with a healthcare professional before taking OXA 50MG INJ, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.
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