Trazumab 150mg

Trazumab 150mg is a medication used to treat certain types of breast cancer, including HER2-positive breast cancer. It is a recombinant humanized monoclonal antibody that works by targeting the HER2 protein on the surface of cancer cells, preventing the growth and spread of cancer.

Composition:

Trazumab 150mg is a solution of Trastuzumab, a monoclonal antibody that is specific to the HER2 protein.

Indications:

Trazumab 150mg is indicated for the treatment of:

• HER2-positive breast cancer in combination with chemotherapy
• HER2-positive metastatic breast cancer
• HER2-positive gastric cancer in combination with chemotherapy

Mechanism of Action:

Trastuzumab works by:

1. Binding to the HER2 protein on the surface of cancer cells
2. Inhibiting the growth and proliferation of cancer cells
3. Preventing the formation of new blood vessels that supply oxygen and nutrients to the tumor

Dosage and Administration:

The recommended dosage of Trazumab 150mg is:

• 150mg administered as an intravenous infusion every 21 days
• The dose should be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Trazumab 150mg include:

1. Fatigue
2. Fever
3. Chills
4. Nausea and vomiting
5. Diarrhea
6. Skin rash
7. Muscle pain

Serious side effects can include:

1. Cardiac toxicity (heart failure, arrhythmias)
2. Pulmonary toxicity (interstitial lung disease)
3. Infusion reactions (hypersensitivity reactions)
4. Hepatotoxicity (liver damage)

Contraindications:

Trazumab 150mg is contraindicated in patients with:

1. Severe hypersensitivity to trastuzumab
2. Severe cardiac disease
3. Severe liver disease
4. Severe kidney disease

Precautions:

1. Patients with a history of cardiac disease should be closely monitored while receiving Trazumab 150mg.
2. Patients with a history of liver disease should be closely monitored while receiving Trazumab 150mg.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of fever, chills, or skin rash.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.

As with any medication, it is important to consult with a healthcare professional before taking Trazumab 150mg, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.