Decapeptyl DEPOT 3.75mg

Decapeptyl DEPOT is a medication used to treat various types of cancer, including prostate cancer, breast cancer, and ovarian cancer. It is a sterile injection containing Triptorelin, a luteinizing hormone-releasing hormone (LHRH) agonist that works by suppressing the production of gonadotropins and reducing the production of sex hormones.

Composition:

Decapeptyl DEPOT is a sterile injection containing Triptorelin, a LHRH agonist.

Indications:

Decapeptyl DEPOT is indicated for the treatment of:

• Prostate cancer (advanced prostate cancer, locally advanced prostate cancer)
• Breast cancer (advanced breast cancer, metastatic breast cancer)
• Ovarian cancer (advanced ovarian cancer, epithelial ovarian cancer)

Mechanism of Action:

Triptorelin works by:

1. Binding to the LHRH receptor on the pituitary gland
2. Suppressing the release of gonadotropins (LH and FSH)
3. Reducing the production of sex hormones (testosterone and estrogen)
4. Inhibiting the growth and proliferation of cancer cells

Dosage and Administration:

The recommended dosage of Decapeptyl DEPOT is:

• 3.75mg administered as an intramuscular injection every 28 days
• The dose should be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Decapeptyl DEPOT include:

1. Hot flashes
2. Increased risk of cardiovascular events
3. Nausea and vomiting
4. Fatigue
5. Joint pain
6. Headache
7. Dizziness

Serious side effects can include:

1. Hypersensitivity reactions (anaphylaxis)
2. Infusion-related reactions (chest tightness, difficulty breathing)
3. Cardiovascular events (heart attack, stroke)
4. Gastrointestinal perforation

Contraindications:

Decapeptyl DEPOT is contraindicated in patients with:

1. Severe hypersensitivity reactions to Triptorelin or any component of the formulation
2. Severe liver disease
3. Severe kidney disease

Precautions:

1. Patients with a history of cardiovascular disease should be closely monitored while receiving Decapeptyl DEPOT.
2. Patients with a history of liver disease should be closely monitored while receiving Decapeptyl DEPOT.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of hot flashes, nausea, vomiting, or joint pain.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.

As with any medication, it is important to consult with a healthcare professional before taking Decapeptyl DEPOT, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.