Cytarine 100 is a medication used to treat various types of cancer, including acute lymphoblastic leukemia, acute myeloid leukemia, and lymphoma. It is a sterile injection containing Cytarabine, a nucleoside analog that works by inhibiting the synthesis of DNA and RNA.
Composition:
Cytarine 100 is a sterile injection containing Cytarabine, a nucleoside analog.
Indications:
Cytarine 100 is indicated for the treatment of:
- Acute lymphoblastic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Lymphoma (non-Hodgkin’s lymphoma, Hodgkin’s lymphoma)
Mechanism of Action:
Cytarabine works by:
- Inhibiting the enzyme cytidine kinase, which is necessary for DNA synthesis
- Inhibiting the synthesis of DNA and RNA
- Inducing apoptosis (cell death) in cancer cells
Dosage and Administration:
The recommended dosage of Cytarine 100 is:
- 100mg administered as an intravenous infusion over 60-120 minutes every 12 hours
- The dose should be adjusted based on the patient’s response to treatment and tolerability
Side Effects:
Common side effects of Cytarine 100 include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Headache
- Dizziness
- Abdominal pain
- Constipation
Serious side effects can include:
- Bone marrow suppression (anemia, thrombocytopenia, neutropenia)
- Infections (sepsis, pneumonia)
- Cardiac toxicity (arrhythmias, heart failure)
- Neurotoxicity (seizures, coma)
Contraindications:
Cytarine 100 is contraindicated in patients with:
- Severe hypersensitivity reactions to Cytarabine or any component of the formulation
- Severe liver disease
- Severe kidney disease
Precautions:
- Patients with a history of cardiac disease should be closely monitored while receiving Cytarine 100.
- Patients with a history of liver disease should be closely monitored while receiving Cytarine 100.
Patient Counseling:
- Patients should be counseled on the importance of taking their medication as directed and not missing doses.
- Patients should be instructed to report any signs of nausea, vomiting, diarrhea, or abdominal pain.
- Patients should be advised to report any changes in their appetite or weight loss.
Storage and Handling:
- Store at room temperature (20°C to 25°C) and protected from light.
- Do not freeze or expose to direct sunlight.
- Use within 24 months of opening.
Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.
As with any medication, it is important to consult with a healthcare professional before taking Cytarine 100, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.
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