Giloz 250mg

Giloz 250mg is a medication used to treat certain types of brain cancer, including glioblastoma and anaplastic astrocytoma. It is an oral medication that works by inhibiting the growth of cancer cells and slowing down the progression of the disease.

Composition:

Giloz 250mg contains Temozolomide, a medication that is an alkylating agent.

Indications:

Giloz 250mg is indicated for the treatment of:

1. Glioblastoma (brain cancer) in combination with radiation therapy
2. Anaplastic astrocytoma (brain cancer) in combination with radiation therapy

Mechanism of Action:

Temozolomide works by:

1. Inhibiting the growth of cancer cells by damaging their DNA
2. Interfering with the repair of damaged DNA
3. Inducing apoptosis (cell death) in cancer cells

Dosage and Administration:

The recommended dosage of Giloz 250mg is:

• 250mg taken orally once daily, on a specific schedule, as determined by your healthcare provider
• The dose should be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Giloz 250mg include:

1. Nausea and vomiting
2. Fatigue
3. Hair loss
4. Dizziness
5. Stomach pain
6. Headache
7. Skin rash

Serious side effects can include:

1. Bone marrow suppression (low white blood cell count)
2. Increased risk of bleeding
3. Increased risk of infection
4. Liver damage

Contraindications:

Giloz 250mg is contraindicated in patients with:

1. Hypersensitivity to Temozolomide or other alkylating agents
2. Severe kidney disease
3. Severe liver disease

Precautions:

1. Patients with a history of cardiac disease should be closely monitored while receiving Giloz 250mg.
2. Patients with a history of kidney disease should be closely monitored while receiving Giloz 250mg.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea or vomiting.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.

As with any medication, it is important to consult with a healthcare professional before taking Giloz 250mg, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.