Lenangio 15 is a medication used to treat certain types of cancer, including multiple myeloma, follicular lymphoma, and mantle cell lymphoma. It is a capsule that works by blocking the action of proteins that help cancer cells grow and multiply.
Composition:
Lenangio 15 contains Lenalidomide, a medication that is a thalidomide analog.
Indications:
Lenangio 15 is indicated for the treatment of:
- Multiple myeloma (a type of blood cancer) in combination with dexamethasone
- Mantle cell lymphoma (a type of blood cancer) in patients who have received at least one prior therapy
- Follicular lymphoma (a type of blood cancer) in patients who have received at least one prior therapy
Mechanism of Action:
Lenalidomide works by:
- Blocking the action of proteins that help cancer cells grow and multiply
- Activating the immune system to attack cancer cells
- Reducing the production of certain cytokines that promote inflammation
Dosage and Administration:
The recommended dosage of Lenangio 15 is:
- 15mg taken orally once daily, in combination with dexamethasone
- The dose should be adjusted based on the patient’s response to treatment and tolerability
Side Effects:
Common side effects of Lenangio 15 include:
- Fatigue
- Nausea and vomiting
- Headache
- Dizziness
- Constipation
- Diarrhea
- Skin rash
Serious side effects can include:
- Thrombocytopenia (low platelet count)
- Neutropenia (low white blood cell count)
- Anemia (low red blood cell count)
- Hematologic toxicity (toxicity to the blood cells)
- Increased risk of infections
Contraindications:
Lenangio 15 is contraindicated in patients with:
- Hypersensitivity to Lenalidomide or other thalidomide analogs
- Severe allergic reactions to human serum albumin or other components of the medication
Precautions:
- Patients with a history of cardiac disease should be closely monitored while receiving Lenangio 15.
- Patients with a history of kidney disease should be closely monitored while receiving Lenangio 15.
Patient Counseling:
- Patients should be counseled on the importance of taking their medication as directed and not missing doses.
- Patients should be instructed to report any signs of fatigue or nausea.
- Patients should be advised to report any changes in their appetite or weight loss.
Storage and Handling:
- Store at room temperature (20°C to 25°C) and protected from light.
- Do not freeze or expose to direct sunlight.
- Use within 24 months of opening.
Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.
As with any medication, it is important to consult with a healthcare professional before taking Lenangio 15, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.
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