Giloz 20mg

Giloz 20mg is a medication used to treat certain types of brain cancer, including glioblastoma multiforme and anaplastic astrocytoma. It is a capsule that works by damaging the DNA of cancer cells, making it difficult for them to grow and multiply.

Composition:

Giloz 20mg contains Temozolomide, a medication that is an oral alkylating agent.

Indications:

Giloz 20mg is indicated for the treatment of:

1. Glioblastoma multiforme (a type of brain cancer) in combination with radiotherapy
2. Anaplastic astrocytoma (a type of brain cancer) in combination with radiotherapy

Mechanism of Action:

Temozolomide works by:

1. Damaging the DNA of cancer cells, making it difficult for them to grow and multiply
2. Inhibiting the repair of damaged DNA, making it more difficult for cancer cells to survive
3. Activating the immune system to attack cancer cells

Dosage and Administration:

The recommended dosage of Giloz 20mg is:

• 20mg taken orally once daily, in combination with radiotherapy
• The dose should be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Giloz 20mg include:

1. Nausea and vomiting
2. Fatigue
3. Headache
4. Dizziness
5. Hair loss
6. Skin rash
7. Stomach pain

Serious side effects can include:

1. Bone marrow suppression (reduced production of blood cells)
2. Increased risk of infections
3. Seizures
4. Pneumonia

Contraindications:

Giloz 20mg is contraindicated in patients with:

1. Hypersensitivity to Temozolomide or other alkylating agents
2. Severe allergic reactions to human serum albumin or other components of the medication

Precautions:

1. Patients with a history of cardiac disease should be closely monitored while receiving Giloz 20mg.
2. Patients with a history of kidney disease should be closely monitored while receiving Giloz 20mg.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea or vomiting.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.

As with any medication, it is important to consult with a healthcare professional before taking Giloz 20mg, especially if you have a history of medical conditions, are taking other medications, or are pregnant or breastfeeding.