Octride DEPOT 30 is a prescription medication used to treat certain types of cancer, including carcinoid tumors and metastatic glucagonoma. It is a synthetic analog of somatostatin, which is a hormone that helps to regulate various bodily functions.
Composition:
- Octreotide 30mg/mL
Mechanism of Action:
Octreotide works by:
- Binding to somatostatin receptors on the surface of cancer cells, which can help to slow down the growth and proliferation of these cells
- Inhibiting the release of hormones that can stimulate the growth of cancer cells
- Reducing the symptoms associated with carcinoid tumors, such as diarrhea and flushing
Indications:
Octride DEPOT 30 is approved for the treatment of:
- Carcinoid tumors, including those that are unresectable or metastatic
- Metastatic glucagonoma, a type of pancreatic cancer that secretes excessive amounts of glucagon
- Acromegaly, a condition caused by excess growth hormone production
Dosage:
The recommended dosage of Octride DEPOT 30 is:
- 30mg administered as an intramuscular injection every 4 weeks
- The recommended duration of treatment is until disease progression or unacceptable toxicity occurs
Side Effects:
Common side effects of Octride DEPOT 30 include:
- Pain or swelling at the injection site
- Nausea and vomiting
- Abdominal pain
- Diarrhea
- Headache
- Fatigue
- Muscle weakness
- Increased risk of infections
Recommendation:
Octride DEPOT 30 is recommended for patients with carcinoid tumors, metastatic glucagonoma, or acromegaly who have not responded to other treatments.
Important Note:
- Patients taking Octride DEPOT 30 should be closely monitored for signs of liver toxicity or gallstones.
- Patients taking Octride DEPOT 30 should avoid taking medications that may interact with it, such as blood thinners or medications that can increase the risk of bleeding.
- Pregnant or breastfeeding women should not use Octride DEPOT 30, as it may harm the fetus or infant.
- Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Octride DEPOT 30 and to detect any potential side effects or complications.
Special Precautions:
- Patients with a history of liver disease or kidney disease should be closely monitored while taking Octride DEPOT 30.
- Patients with a history of gallstones should be closely monitored while taking Octride DEPOT 30.
Contraindications:
- Patients who are allergic to octreotide or any other component of Octride DEPOT 30 should not use it.
- Patients who are pregnant or breastfeeding should not use Octride DEPOT 30.
- Patients with severe liver disease or severe kidney disease should not use Octride DEPOT 30.
Warnings:
- Octride DEPOT 30 can cause liver toxicity, which can lead to elevated liver enzymes and liver damage.
- Patients with a history of liver disease should be closely monitored while taking Octride DEPOT 30.
- Patients should report any changes in their liver function tests or symptoms of liver toxicity to their healthcare provider immediately.
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