Soranib 200mg

Soranib is a medication used to treat certain types of cancer, including liver cancer, kidney cancer, and thyroid cancer. It is a kinase inhibitor that works by blocking the growth of cancer cells. Here are some key points about the product:

Composition:

Soranib contains Sorafenib, a kinase inhibitor that is used to treat cancer.

Indications:

Soranib is indicated for the treatment of:

1. Hepatocellular carcinoma (liver cancer) in patients who have not received prior chemotherapy
2. Renal cell carcinoma (kidney cancer) in patients who have received prior nephrectomy and are at high risk of recurrence
3. Differentiated thyroid carcinoma (thyroid cancer) that has spread to other parts of the body

Mechanism of Action:

Soranib works by:

1. Inhibiting the growth of cancer cells by blocking the activity of multiple kinases, including RAF, VEGFR, and PDGFR
2. Reducing the production of vascular endothelial growth factor (VEGF), which is a protein that helps tumors grow new blood vessels

Dosage and Administration: The recommended dosage of Soranib is:

• 400mg administered as a tablet twice daily, with food
• The dose should be taken at the same time each day, with or without food

Side Effects:

Common side effects of Soranib include:

1. Rash or skin reaction
2. Fatigue
3. Diarrhea
4. Nausea and vomiting
5. Hair loss
6. Abdominal pain
7. Increased risk of bleeding or bruising
8. Increased risk of liver damage

Serious side effects can include:

1. Hypertension (high blood pressure)
2. Cardiac arrhythmias (abnormal heart rhythms)
3. Blood clotting disorders
4. Pancreatitis (inflammation of the pancreas)
5. Kidney damage

Contraindications:

Soranib is contraindicated in patients with:

1. Hypersensitivity to Sorafenib
2. Severe kidney or liver disease
3. Active bleeding or bleeding disorder
4. Pregnancy or breastfeeding

Precautions:

1. Patients with a history of kidney or liver disease should be closely monitored while receiving Soranib.
2. Patients with a history of bleeding or bleeding disorders should be closely monitored while receiving Soranib.
3. Patients with a history of cardiac arrhythmias should be closely monitored while receiving Soranib.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of rash or skin reaction.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.