Xbira 500 mg

Xbira 500 mg is a medication used to treat certain types of prostate cancer, specifically metastatic castration-resistant prostate cancer (mCRPC). It is an oral medication that works by blocking the production of androgens, which are hormones that can stimulate the growth of cancer cells. Here are some key points about the product:

Composition:

Xbira 500 mg contains Abiraterone, a medication that blocks the production of androgens in the body.

Indications:

Xbira 500 mg is indicated for the treatment of:

1. Metastatic castration-resistant prostate cancer (mCRPC) in patients who have received previous chemotherapy
2. Locally advanced, metastatic, or recurrent prostate cancer in patients who have received previous androgen-deprivation therapy

Mechanism of Action:

Abiraterone works by:

1. Inhibiting the enzyme CYP17, which is necessary for the production of androgens in the body
2. Reducing the production of androgens, such as testosterone, which can stimulate the growth of cancer cells

Dosage and Administration: The recommended dosage of Xbira 500 mg is:

• 1 tablet (500mg) taken orally once daily, with or without food
• The dose should be taken at the same time each day
• The medication should be taken continuously until disease progression or unacceptable toxicity

Side Effects:

Common side effects of Xbira 500 mg include:

1. Adrenal insufficiency (a condition where the adrenal glands do not produce enough hormones)
2. Hypokalemia (low levels of potassium in the blood)
3. Fatigue
4. Muscle weakness
5. Nausea and vomiting
6. Diarrhea
7. Edema (swelling)
8. Increased risk of fractures

Serious side effects can include:

1. Hypertension (high blood pressure)
2. Cardiac arrhythmias (abnormal heart rhythms)
3. Blood clotting disorders
4. Pancreatitis (inflammation of the pancreas)
5. Severe allergic reactions

Contraindications:

Xbira 500 mg is contraindicated in patients with:

1. Hypersensitivity to Abiraterone
2. Pregnancy or breastfeeding
3. Severe liver or kidney disease
4. Active bleeding or bleeding disorder

Precautions:

1. Patients with a history of adrenal insufficiency should be closely monitored while receiving Xbira 500 mg.
2. Patients with a history of kidney or liver disease should be closely monitored while receiving Xbira 500 mg.
3. Patients with a history of bleeding or bleeding disorders should be closely monitored while receiving Xbira 500 mg.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of adrenal insufficiency or hypokalemia.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from light.
• Do not freeze or expose to direct sunlight.
• Use within 24 months of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.