Celofos 1000mg

Celofos is a medication used to treat various types of cancer, including testicular cancer, ovarian cancer, and soft tissue sarcoma. It is a chemotherapy medication that is used to treat cancer. Here are some key points about the product:

Composition:

Celofos contains Ifosfamide, a chemotherapy medication that is used to treat cancer.

Indications:

Celofos is indicated for the treatment of:

1. Testicular cancer (metastatic or non-metastatic)
2. Ovarian cancer (metastatic or non-metastatic)
3. Soft tissue sarcoma (metastatic or non-metastatic)
4. Lymphoma
5. Germ cell tumors

Mechanism of Action:

Ifosfamide works by:

1. Interfering with DNA synthesis and repair
2. Inhibiting the growth of cancer cells
3. Causing cell death

Dosage and Administration: The recommended dosage of Celofos is:

• 2g administered as a slow intravenous injection over 30-60 minutes
• The dose may be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Celofos include:

1. Nausea and vomiting
2. Diarrhea
3. Fatigue
4. Hair loss
5. Low blood cell count (neutropenia, thrombocytopenia)
6. Increased risk of infections
7. Gastrointestinal toxicity

Serious side effects can include:

1. Severe allergic reactions
2. Bone marrow suppression
3. Pneumonia
4. Hemorrhagic cystitis
5. Pulmonary toxicity
6. Hepatotoxicity

Contraindications:

Celofos is contraindicated in patients with:

1. Hypersensitivity to Ifosfamide
2. Severe kidney impairment
3. Severe liver impairment
4. Pregnancy or breastfeeding

Precautions:

1. Patients with a history of cardiac disease or cardiovascular risk factors should be closely monitored while receiving Celofos.
2. Patients with a history of kidney disease or liver impairment should be closely monitored while receiving Celofos.
3. Patients with a history of bleeding disorders should be closely monitored while receiving Celofos.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea, vomiting, or diarrhea.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from moisture.
• Do not freeze or expose to direct sunlight.
• Use within 24 hours of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.