Celdaz 200mg

Celdaz is a medication used to treat various types of cancer, including Hodgkin lymphoma, non-Hodgkin lymphoma, and melanoma. Here are some key points about the product:

Composition:

Celdaz contains Dacarbazine, a chemotherapeutic agent that is used to treat various types of cancer.

Indications:

Celdaz is indicated for the treatment of:

1. Hodgkin lymphoma
2. Non-Hodgkin lymphoma
3. Malignant melanoma

Mechanism of Action:

Dacarbazine works by:

1. Inhibiting the activity of DNA repair enzymes
2. Inducing apoptosis (cell death) in cancer cells
3. Inhibiting the growth of new blood vessels that supply tumors

Dosage and Administration:

The recommended dosage of Celdaz is:

• 500mg administered as an intravenous infusion over 30 minutes to 1 hour every 3-4 weeks
• The dose may be adjusted based on the patient’s response to treatment and tolerability

Side Effects:

Common side effects of Celdaz include:

1. Nausea and vomiting
2. Fatigue
3. Hair loss
4. Diarrhea
5. Constipation
6. Headache

Serious side effects can include:

1. Severe allergic reactions
2. Hemolytic anemia
3. Thrombocytopenia (low platelet count)
4. Pulmonary toxicity
5. Cardiac toxicity

Contraindications:

Celdaz is contraindicated in patients with:

1. Hypersensitivity to Dacarbazine
2. Pregnancy or breastfeeding
3. Active or suspected infections

Precautions:

1. Patients with a history of cardiac disease or cardiac dysfunction should be closely monitored while receiving Celdaz.
2. Patients with a history of liver disease or liver impairment should be closely monitored while receiving Celdaz.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of nausea, vomiting, or fatigue.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from moisture.
• Do not freeze or expose to direct sunlight.
• Use within 24 hours of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.